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Intranasal delivery of mouse [D-Leu-4]-OB3, a synthetic peptide amide with leptin-like activity, improves energy balance, glycaemic control, insulin sensitivity and bone formation in leptin-resistant C57BLK/6-m db/db mice.
Waldrop MA, Leinung MC, Lee DW, Grasso P. Waldrop MA, et al. Among authors: leinung mc. Diabetes Obes Metab. 2010 Oct;12(10):871-5. doi: 10.1111/j.1463-1326.2010.01243.x. Diabetes Obes Metab. 2010. PMID: 20920039
In vivo effects of leptin-related synthetic peptides on body weight and food intake in female ob/ob mice: localization of leptin activity to domains between amino acid residues 106-140.
Grasso P, Leinung MC, Ingher SP, Lee DW. Grasso P, et al. Among authors: leinung mc. Endocrinology. 1997 Apr;138(4):1413-8. doi: 10.1210/endo.138.4.5087. Endocrinology. 1997. PMID: 9075696
Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis, and thermoregulation.
Rozhavskaya-Arena M, Lee DW, Leinung MC, Grasso P. Rozhavskaya-Arena M, et al. Among authors: leinung mc. Endocrinology. 2000 Jul;141(7):2501-7. doi: 10.1210/endo.141.7.7556. Endocrinology. 2000. PMID: 10875251
[D-LEU-4]-OB3, a synthetic leptin agonist, improves hyperglycemic control in C57BL/6J ob/ob mice.
Grasso P, Rozhavskaya-Arena M, Leinung MC, Lee DW. Grasso P, et al. Among authors: leinung mc. Regul Pept. 2001 Sep 15;101(1-3):123-9. doi: 10.1016/s0167-0115(01)00274-9. Regul Pept. 2001. PMID: 11495687
Oral delivery of mouse [d-Leu-4]-OB3, a synthetic peptide amide with leptin-like activity, in male C57BL/6J wild-type and ob/ob mice: effects on energy balance, glycaemic control and serum osteocalcin levels.
Novakovic ZM, Leinung MC, Lee DW, Grasso P. Novakovic ZM, et al. Among authors: leinung mc. Diabetes Obes Metab. 2010 Jun;12(6):532-9. doi: 10.1111/j.1463-1326.2009.01189.x. Diabetes Obes Metab. 2010. PMID: 20518808
Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor.
Grasso P, White DW, Tartaglia LA, Leinung MC, Lee DW. Grasso P, et al. Among authors: leinung mc. Diabetes. 1999 Nov;48(11):2204-9. doi: 10.2337/diabetes.48.11.2204. Diabetes. 1999. PMID: 10535455
Epitope mapping of secreted mouse leptin utilizing peripherally administered synthetic peptides.
Grasso P, Leinung MC, Lee DW. Grasso P, et al. Among authors: leinung mc. Regul Pept. 1999 Dec 23;85(2-3):93-100. doi: 10.1016/s0167-0115(99)00082-8. Regul Pept. 1999. PMID: 10651062
Benefits of short-term professional continuous glucose monitoring in clinical practice.
Leinung M, Nardacci E, Patel N, Bettadahalli S, Paika K, Thompson S. Leinung M, et al. Diabetes Technol Ther. 2013 Sep;15(9):744-7. doi: 10.1089/dia.2013.0027. Epub 2013 Jun 20. Diabetes Technol Ther. 2013. PMID: 23786229
[D-Leu-4]-OB3, an orally bioavailable leptin-related synthetic peptide insulin sensitizer: a study comparing the efficacies of [D-Leu-4]-OB3 and metformin on energy balance and glycemic regulation in insulin-deficient male Swiss Webster mice.
Novakovic ZM, Leinung MC, Grasso P. Novakovic ZM, et al. Among authors: leinung mc. Peptides. 2013 May;43:167-73. doi: 10.1016/j.peptides.2013.02.023. Epub 2013 Mar 7. Peptides. 2013. PMID: 23500518
Use of insulin pump therapy in patients with type 2 diabetes after failure of multiple daily injections.
Leinung MC, Thompson S, Luo M, Leykina L, Nardacci E. Leinung MC, et al. Endocr Pract. 2013 Jan-Feb;19(1):9-13. doi: 10.4158/EP12104.OR. Endocr Pract. 2013. PMID: 22982794
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