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Page 1
Estrogen Production in Pancreatic Cancer Shapes a Tumor-Suppressive Stromal Microenvironment.
Manoukian P, van Schie DM, van Schelt AS, Wassenaar NPM, Dings MPG, Lansbergen MF, Waasdorp C, Leite de Oliveira R, Wickenhagen WV, Heijboer AC, Koster J, Zwijnenburg DA, Farina-Sarasqueta A, Kazemier G, Wilmink JW, Medema JP, van Laarhoven HWM, Bijlsma MF. Manoukian P, et al. Among authors: leite de oliveira r. Cancer Res. 2026 Feb 2;86(3):571-586. doi: 10.1158/0008-5472.CAN-24-4707. Cancer Res. 2026. PMID: 41258799 Free PMC article.
With great power comes great vulnerability.
Leite de Oliveira R, Wang L, Bernards R. Leite de Oliveira R, et al. Mol Cell Oncol. 2018 Oct 9;5(6):e1509488. doi: 10.1080/23723556.2018.1509488. eCollection 2018. Mol Cell Oncol. 2018. PMID: 30525088 Free PMC article.
Anti-cancer therapy: senescence is the new black.
Leite de Oliveira R, Bernards R. Leite de Oliveira R, et al. EMBO J. 2018 May 15;37(10):e99386. doi: 10.15252/embj.201899386. Epub 2018 Apr 18. EMBO J. 2018. PMID: 29669859 Free PMC article.
Genetic and compound screens uncover factors modulating cancer cell response to indisulam.
Pogacar Z, Groot K, Jochems F, Dos Santos Dias M, Mulero-Sánchez A, Morris B, Roosen M, Wardak L, De Conti G, Velds A, Lieftink C, Thijssen B, Beijersbergen RL, Bernards R, Leite de Oliveira R. Pogacar Z, et al. Among authors: leite de oliveira r. Life Sci Alliance. 2022 May 9;5(9):e202101348. doi: 10.26508/lsa.202101348. Print 2022 Sep. Life Sci Alliance. 2022. PMID: 35534224 Free PMC article.
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.
Pogacar Z, Johnson JL, Krenning L, De Conti G, Jochems F, Lieftink C, Velds A, Wardak L, Groot K, Schepers A, Wang L, Song JY, van de Ven M, van Tellingen O, Medema RH, Beijersbergen RL, Bernards R, Leite de Oliveira R. Pogacar Z, et al. Among authors: leite de oliveira r. PLoS One. 2022 Sep 6;17(9):e0273182. doi: 10.1371/journal.pone.0273182. eCollection 2022. PLoS One. 2022. PMID: 36067171 Free PMC article.
The Cancer SENESCopedia: A delineation of cancer cell senescence.
Jochems F, Thijssen B, De Conti G, Jansen R, Pogacar Z, Groot K, Wang L, Schepers A, Wang C, Jin H, Beijersbergen RL, Leite de Oliveira R, Wessels LFA, Bernards R. Jochems F, et al. Among authors: leite de oliveira r. Cell Rep. 2021 Jul 27;36(4):109441. doi: 10.1016/j.celrep.2021.109441. Cell Rep. 2021. PMID: 34320349 Free PMC article.
An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential.
Wang L, Leite de Oliveira R, Huijberts S, Bosdriesz E, Pencheva N, Brunen D, Bosma A, Song JY, Zevenhoven J, Los-de Vries GT, Horlings H, Nuijen B, Beijnen JH, Schellens JHM, Bernards R. Wang L, et al. Among authors: leite de oliveira r. Cell. 2018 May 31;173(6):1413-1425.e14. doi: 10.1016/j.cell.2018.04.012. Epub 2018 May 10. Cell. 2018. PMID: 29754815 Free article.
A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in BRAFV600-Mutated Melanoma.
Embaby A, Huijberts SCFA, Wang L, Leite de Oliveira R, Rosing H, Nuijen B, Sanders J, Hofland I, van Steenis C, Kluin RJC, Lieftink C, Smith CG, Blank CU, van Thienen JV, Haanen JBAG, Steeghs N, Opdam FL, Beijnen JH, Huitema ADR, Bernards R, Schellens JHM, Wilgenhof S. Embaby A, et al. Among authors: leite de oliveira r. Clin Cancer Res. 2024 Aug 1;30(15):3157-3166. doi: 10.1158/1078-0432.CCR-23-3171. Clin Cancer Res. 2024. PMID: 38739109
16 results