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Protein kinase C beta is dispensable for TCR-signaling.
Thuille N, Gruber T, Böck G, Leitges M, Baier G. Thuille N, et al. Among authors: leitges m. Mol Immunol. 2004 Jun;41(4):385-90. doi: 10.1016/j.molimm.2004.03.007. Mol Immunol. 2004. PMID: 15163535
Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4+ T lymphocyte activation.
Siegmund K, Thuille N, Posch N, Fresser F, Leitges M, Baier G. Siegmund K, et al. Among authors: leitges m. Cell Commun Signal. 2019 May 28;17(1):56. doi: 10.1186/s12964-019-0364-0. Cell Commun Signal. 2019. PMID: 31138259 Free PMC article.
PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes.
Thuille N, Wachowicz K, Hermann-Kleiter N, Kaminski S, Fresser F, Lutz-Nicoladoni C, Leitges M, Thome M, Massoumi R, Baier G. Thuille N, et al. Among authors: leitges m. PLoS One. 2013;8(1):e53709. doi: 10.1371/journal.pone.0053709. Epub 2013 Jan 15. PLoS One. 2013. PMID: 23335970 Free PMC article.
PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo.
Gruber T, Hermann-Kleiter N, Pfeifhofer-Obermair C, Lutz-Nicoladoni C, Thuille N, Letschka T, Barsig J, Baudler M, Li J, Metzler B, Nüsslein-Hildesheim B, Wagner J, Leitges M, Baier G. Gruber T, et al. Among authors: leitges m. Mol Immunol. 2009 Jun;46(10):2071-9. doi: 10.1016/j.molimm.2009.02.030. Epub 2009 Apr 7. Mol Immunol. 2009. PMID: 19356803
PKC-theta selectively controls the adhesion-stimulating molecule Rap1.
Letschka T, Kollmann V, Pfeifhofer-Obermair C, Lutz-Nicoladoni C, Obermair GJ, Fresser F, Leitges M, Hermann-Kleiter N, Kaminski S, Baier G. Letschka T, et al. Among authors: leitges m. Blood. 2008 Dec 1;112(12):4617-27. doi: 10.1182/blood-2007-11-121111. Epub 2008 Sep 16. Blood. 2008. PMID: 18796635
Defective IgG2a/2b class switching in PKC alpha-/- mice.
Pfeifhofer C, Gruber T, Letschka T, Thuille N, Lutz-Nicoladoni C, Hermann-Kleiter N, Braun U, Leitges M, Baier G. Pfeifhofer C, et al. Among authors: leitges m. J Immunol. 2006 May 15;176(10):6004-11. doi: 10.4049/jimmunol.176.10.6004. J Immunol. 2006. PMID: 16670309
Mechanical stress-activated PKCdelta regulates smooth muscle cell migration.
Li C, Wernig F, Leitges M, Hu Y, Xu Q. Li C, et al. Among authors: leitges m. FASEB J. 2003 Nov;17(14):2106-8. doi: 10.1096/fj.03-0150fje. Epub 2003 Sep 4. FASEB J. 2003. PMID: 12958154
Phosphorylation of the Stat1 transactivating domain is required for the response to type I interferons.
Pilz A, Ramsauer K, Heidari H, Leitges M, Kovarik P, Decker T. Pilz A, et al. Among authors: leitges m. EMBO Rep. 2003 Apr;4(4):368-73. doi: 10.1038/sj.embor.embor802. Epub 2003 Mar 21. EMBO Rep. 2003. PMID: 12671680 Free PMC article.
Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells.
Pfeifhofer C, Kofler K, Gruber T, Tabrizi NG, Lutz C, Maly K, Leitges M, Baier G. Pfeifhofer C, et al. Among authors: leitges m. J Exp Med. 2003 Jun 2;197(11):1525-35. doi: 10.1084/jem.20020234. J Exp Med. 2003. PMID: 12782715 Free PMC article.
Surfactant protein A activation of atypical protein kinase C zeta in IkappaB-alpha-dependent anti-inflammatory immune regulation.
Moulakakis C, Adam S, Seitzer U, Schromm AB, Leitges M, Stamme C. Moulakakis C, et al. Among authors: leitges m. J Immunol. 2007 Oct 1;179(7):4480-91. doi: 10.4049/jimmunol.179.7.4480. J Immunol. 2007. PMID: 17878344
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