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Development of Dl1.72, a Novel Anti-DLL1 Antibody with Anti-Tumor Efficacy against Estrogen Receptor-Positive Breast Cancer.
Silva G, Sales-Dias J, Casal D, Alves S, Domenici G, Barreto C, Matos C, Lemos AR, Matias AT, Kucheryava K, Ferreira A, Moita MR, Braga S, Brito C, Cabral MG, Casalou C, Barral DC, Sousa PMF, Videira PA, Bandeiras TM, Barbas A. Silva G, et al. Among authors: lemos ar. Cancers (Basel). 2021 Aug 13;13(16):4074. doi: 10.3390/cancers13164074. Cancers (Basel). 2021. PMID: 34439228 Free PMC article.
Production of high-quality SARS-CoV-2 antigens: Impact of bioprocess and storage on glycosylation, biophysical attributes, and ELISA serologic tests performance.
Castro R, Nobre LS, Eleutério RP, Thomaz M, Pires A, Monteiro SM, Mendes S, Gomes RA, Clemente JJ, Sousa MFQ, Pinto F, Silva AC, Freitas MC, Lemos AR, Akpogheneta O, Kosack L, Bergman ML, Duarte N, Matoso P, Costa J, Bandeiras TM, Gomes-Alves P, Gonçalves CP, Demengeot J, Alves PM. Castro R, et al. Among authors: lemos ar. Biotechnol Bioeng. 2021 Jun;118(6):2202-2219. doi: 10.1002/bit.27725. Epub 2021 Mar 27. Biotechnol Bioeng. 2021. PMID: 33624859 Free PMC article.
Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors.
Seixas JD, Sousa BB, Marques MC, Guerreiro A, Traquete R, Rodrigues T, Albuquerque IS, Sousa MFQ, Lemos AR, Sousa PMF, Bandeiras TM, Wu D, Doyle SK, Robinson CV, Koehler AN, Corzana F, Matias PM, Bernardes GJL. Seixas JD, et al. Among authors: lemos ar. RSC Chem Biol. 2020 Aug 28;1(4):251-262. doi: 10.1039/d0cb00033g. eCollection 2020 Oct 1. RSC Chem Biol. 2020. PMID: 34458764 Free PMC article.
Optimization of TEAD P-Site Binding Fragment Hit into In Vivo Active Lead MSC-4106.
Heinrich T, Peterson C, Schneider R, Garg S, Schwarz D, Gunera J, Seshire A, Kötzner L, Schlesiger S, Musil D, Schilke H, Doerfel B, Diehl P, Böpple P, Lemos AR, Sousa PMF, Freire F, Bandeiras TM, Carswell E, Pearson N, Sirohi S, Hooker M, Trivier E, Broome R, Balsiger A, Crowden A, Dillon C, Wienke D. Heinrich T, et al. Among authors: lemos ar. J Med Chem. 2022 Jul 14;65(13):9206-9229. doi: 10.1021/acs.jmedchem.2c00403. Epub 2022 Jun 28. J Med Chem. 2022. PMID: 35763499
Extract2Chip-Bypassing Protein Purification in Drug Discovery Using Surface Plasmon Resonance.
Paiva ACF, Lemos AR, Busse P, Martins MT, Silva DO, Freitas MC, Santos SP, Freire F, Barrey EJ, Manival X, Koetzner L, Heinrich T, Wegener A, Grädler U, Bandeiras TM, Schwarz D, Sousa PMF. Paiva ACF, et al. Among authors: lemos ar. Biosensors (Basel). 2023 Oct 5;13(10):913. doi: 10.3390/bios13100913. Biosensors (Basel). 2023. PMID: 37887106 Free PMC article.
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