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Assembly of high-affinity insulin receptor agonists and antagonists from peptide building blocks.
Schäffer L, Brissette RE, Spetzler JC, Pillutla RC, Østergaard S, Lennick M, Brandt J, Fletcher PW, Danielsen GM, Hsiao KC, Andersen AS, Dedova O, Ribel U, Hoeg-Jensen T, Hansen PH, Blume AJ, Markussen J, Goldstein NI. Schäffer L, et al. Among authors: lennick m. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4435-9. doi: 10.1073/pnas.0830026100. Epub 2003 Apr 8. Proc Natl Acad Sci U S A. 2003. PMID: 12684539 Free PMC article.
Peptides identify the critical hotspots involved in the biological activation of the insulin receptor.
Pillutla RC, Hsiao KC, Beasley JR, Brandt J, Østergaard S, Hansen PH, Spetzler JC, Danielsen GM, Andersen AS, Brissette RE, Lennick M, Fletcher PW, Blume AJ, Schäffer L, Goldstein NI. Pillutla RC, et al. Among authors: lennick m. J Biol Chem. 2002 Jun 21;277(25):22590-4. doi: 10.1074/jbc.M202119200. Epub 2002 Apr 18. J Biol Chem. 2002. PMID: 11964401 Free article.
A surrogate-based approach for post-genomic partner identification.
Pillutla RC, Hsiao K, Brissette R, Eder PS, Giordano T, Fletcher PW, Lennick M, Blume AJ, Goldstein NI. Pillutla RC, et al. Among authors: lennick m. BMC Biotechnol. 2001;1:6. doi: 10.1186/1472-6750-1-6. Epub 2001 Sep 25. BMC Biotechnol. 2001. PMID: 11602024 Free PMC article.
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