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Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells.
Fagerli UM, Ullrich K, Stühmer T, Holien T, Köchert K, Holt RU, Bruland O, Chatterjee M, Nogai H, Lenz G, Shaughnessy JD Jr, Mathas S, Sundan A, Bargou RC, Dörken B, Børset M, Janz M. Fagerli UM, et al. Among authors: lenz g. Oncogene. 2011 Jul 14;30(28):3198-206. doi: 10.1038/onc.2011.79. Epub 2011 Apr 11. Oncogene. 2011. PMID: 21478911
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.
Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F, Lenz G, Hanamura I, Wright G, Xiao W, Dave S, Hurt EM, Tan B, Zhao H, Stephens O, Santra M, Williams DR, Dang L, Barlogie B, Shaughnessy JD Jr, Kuehl WM, Staudt LM. Annunziata CM, et al. Among authors: lenz g. Cancer Cell. 2007 Aug;12(2):115-30. doi: 10.1016/j.ccr.2007.07.004. Cancer Cell. 2007. PMID: 17692804 Free PMC article.
Pathogenesis of non-Hodgkin's lymphoma.
Nogai H, Dörken B, Lenz G. Nogai H, et al. Among authors: lenz g. J Clin Oncol. 2011 May 10;29(14):1803-11. doi: 10.1200/JCO.2010.33.3252. Epub 2011 Apr 11. J Clin Oncol. 2011. PMID: 21483013 Review.
MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma.
Wenzel SS, Grau M, Mavis C, Hailfinger S, Wolf A, Madle H, Deeb G, Dörken B, Thome M, Lenz P, Dirnhofer S, Hernandez-Ilizaliturri FJ, Tzankov A, Lenz G. Wenzel SS, et al. Among authors: lenz g, lenz p. Leukemia. 2013 Jun;27(6):1381-90. doi: 10.1038/leu.2012.367. Epub 2012 Dec 21. Leukemia. 2013. PMID: 23257783
The molecular biology of diffuse large B-cell lymphoma.
Frick M, Dörken B, Lenz G. Frick M, et al. Among authors: lenz g. Ther Adv Hematol. 2011 Dec;2(6):369-79. doi: 10.1177/2040620711419001. Ther Adv Hematol. 2011. PMID: 23556103 Free PMC article.
PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer M, Grau M, Lenze D, Wenzel SS, Wolf A, Wollert-Wulf B, Dietze K, Nogai H, Storek B, Madle H, Dörken B, Janz M, Dirnhofer S, Lenz P, Hummel M, Tzankov A, Lenz G. Pfeifer M, et al. Among authors: lenz g, lenz p. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12420-5. doi: 10.1073/pnas.1305656110. Epub 2013 Jul 9. Proc Natl Acad Sci U S A. 2013. PMID: 23840064 Free PMC article.
IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai H, Wenzel SS, Hailfinger S, Grau M, Kaergel E, Seitz V, Wollert-Wulf B, Pfeifer M, Wolf A, Frick M, Dietze K, Madle H, Tzankov A, Hummel M, Dörken B, Scheidereit C, Janz M, Lenz P, Thome M, Lenz G. Nogai H, et al. Among authors: lenz g, lenz p. Blood. 2013 Sep 26;122(13):2242-50. doi: 10.1182/blood-2013-06-508028. Epub 2013 Jul 18. Blood. 2013. PMID: 23869088 Free article.
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.
Kreher S, Bouhlel MA, Cauchy P, Lamprecht B, Li S, Grau M, Hummel F, Köchert K, Anagnostopoulos I, Jöhrens K, Hummel M, Hiscott J, Wenzel SS, Lenz P, Schneider M, Küppers R, Scheidereit C, Giefing M, Siebert R, Rajewsky K, Lenz G, Cockerill PN, Janz M, Dörken B, Bonifer C, Mathas S. Kreher S, et al. Among authors: lenz g, lenz p. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4513-22. doi: 10.1073/pnas.1406985111. Epub 2014 Oct 6. Proc Natl Acad Sci U S A. 2014. PMID: 25288773 Free PMC article.
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma.
Weilemann A, Grau M, Erdmann T, Merkel O, Sobhiafshar U, Anagnostopoulos I, Hummel M, Siegert A, Hayford C, Madle H, Wollert-Wulf B, Fichtner I, Dörken B, Dirnhofer S, Mathas S, Janz M, Emre NC, Rosenwald A, Ott G, Lenz P, Tzankov A, Lenz G. Weilemann A, et al. Among authors: lenz g, lenz p. Blood. 2015 Jan 1;125(1):124-32. doi: 10.1182/blood-2014-08-594507. Epub 2014 Oct 30. Blood. 2015. PMID: 25359993 Free article.
596 results