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Improved prediction of immune checkpoint blockade efficacy across multiple cancer types.
Chowell D, Yoo SK, Valero C, Pastore A, Krishna C, Lee M, Hoen D, Shi H, Kelly DW, Patel N, Makarov V, Ma X, Vuong L, Sabio EY, Weiss K, Kuo F, Lenz TL, Samstein RM, Riaz N, Adusumilli PS, Balachandran VP, Plitas G, Ari Hakimi A, Abdel-Wahab O, Shoushtari AN, Postow MA, Motzer RJ, Ladanyi M, Zehir A, Berger MF, Gönen M, Morris LGT, Weinhold N, Chan TA. Chowell D, et al. Among authors: lenz tl. Nat Biotechnol. 2022 Apr;40(4):499-506. doi: 10.1038/s41587-021-01070-8. Epub 2021 Nov 1. Nat Biotechnol. 2022. PMID: 34725502 Free PMC article.
The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders.
Pagliuca S, Gurnari C, Awada H, Kishtagari A, Kongkiatkamon S, Terkawi L, Zawit M, Guan Y, LaFramboise T, Jha BK, Patel BJ, Hamilton BK, Majhail NS, Lundgren S, Mustjoki S, Saunthararajah Y, Visconte V, Chan TA, Yang CY, Lenz TL, Maciejewski JP. Pagliuca S, et al. Among authors: lenz tl. Blood. 2021 Dec 30;138(26):2781-2798. doi: 10.1182/blood.2021012900. Blood. 2021. PMID: 34748628 Free PMC article.
Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans.
Krause-Kyora B, Nutsua M, Boehme L, Pierini F, Pedersen DD, Kornell SC, Drichel D, Bonazzi M, Möbus L, Tarp P, Susat J, Bosse E, Willburger B, Schmidt AH, Sauter J, Franke A, Wittig M, Caliebe A, Nothnagel M, Schreiber S, Boldsen JL, Lenz TL, Nebel A. Krause-Kyora B, et al. Among authors: lenz tl. Nat Commun. 2018 May 1;9(1):1569. doi: 10.1038/s41467-018-03857-x. Nat Commun. 2018. PMID: 29717136 Free PMC article.
Genome-wide study of a Neolithic Wartberg grave community reveals distinct HLA variation and hunter-gatherer ancestry.
Immel A, Pierini F, Rinne C, Meadows J, Barquera R, Szolek A, Susat J, Böhme L, Dose J, Bonczarowska J, Drummer C, Fuchs K, Ellinghaus D, Kässens JC, Furholt M, Kohlbacher O, Schade-Lindig S, Franke A, Schreiber S, Krause J, Müller J, Lenz TL, Nebel A, Krause-Kyora B. Immel A, et al. Among authors: lenz tl. Commun Biol. 2021 Jan 25;4(1):113. doi: 10.1038/s42003-020-01627-4. Commun Biol. 2021. PMID: 33495542 Free PMC article.
141 results