Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1987 1
1989 1
1991 3
1992 1
1993 2
1994 5
1995 2
1996 5
1997 2
1998 3
1999 2
2000 1
2001 4
2002 6
2003 10
2004 6
2005 7
2006 4
2007 5
2008 5
2009 4
2010 1
2011 2
2012 2
2013 3
2014 6
2015 7
2016 7
2017 3
2018 4
2019 6
2020 2
Text availability
Article attribute
Article type
Publication date

Search Results

114 results
Results by year
Filters applied: . Clear all
Page 1
LINE-1 and EPAS1 DNA methylation associations with high-altitude exposure.
Childebayeva A, Jones TR, Goodrich JM, Leon-Velarde F, Rivera-Chira M, Kiyamu M, Brutsaert TD, Dolinoy DC, Bigham AW. Childebayeva A, et al. Among authors: Leon-Velarde F. Epigenetics. 2019 Jan;14(1):1-15. doi: 10.1080/15592294.2018.1561117. Epub 2019 Jan 9. Epigenetics. 2019. PMID: 30574831 Free PMC article.
Recent discoveries indicate a genetic basis for high-altitude adaptation among human groups who have resided at high altitude for millennia, including Andeans, Tibetans, and Ethiopians. ...Participants recruited at high altitude had lower EPAS1 DNA methylatio …
Recent discoveries indicate a genetic basis for high-altitude adaptation among human groups who have resided at high altitude
Excessive Erythrocytosis and Cardiovascular Risk in Andean Highlanders.
Corante N, Anza-Ramírez C, Figueroa-Mujíca R, Macarlupú JL, Vizcardo-Galindo G, Bilo G, Parati G, Gamboa JL, León-Velarde F, Villafuerte FC. Corante N, et al. Among authors: Leon-Velarde F. High Alt Med Biol. 2018 Sep;19(3):221-231. doi: 10.1089/ham.2017.0123. Epub 2018 May 21. High Alt Med Biol. 2018. PMID: 29782186 Free PMC article.
Life under high-altitude (HA) hypoxic conditions is believed to provide highlanders with a natural protection against cardiovascular and metabolic diseases compared with sea-level inhabitants. ...
Life under high-altitude (HA) hypoxic conditions is believed to provide highlanders with a natural protection against cardiovascular …
The Genetic Architecture of Chronic Mountain Sickness in Peru.
Gazal S, Espinoza JR, Austerlitz F, Marchant D, Macarlupu JL, Rodriguez J, Ju-Preciado H, Rivera-Chira M, Hermine O, Leon-Velarde F, Villafuerte FC, Richalet JP, Gouya L. Gazal S, et al. Among authors: Leon-Velarde F. Front Genet. 2019 Jul 30;10:690. doi: 10.3389/fgene.2019.00690. eCollection 2019. Front Genet. 2019. PMID: 31417607 Free PMC article.
Chronic mountain sickness (CMS) is a pathological condition resulting from chronic exposure to high-altitude hypoxia. While its prevalence is high in native Andeans (>10%), little is known about the genetic architecture of this disease. ...Overall, our results reveal ne …
Chronic mountain sickness (CMS) is a pathological condition resulting from chronic exposure to high-altitude hypoxia. While its preva …
Association of EGLN1 gene with high aerobic capacity of Peruvian Quechua at high altitude.
Brutsaert TD, Kiyamu M, Elias Revollendo G, Isherwood JL, Lee FS, Rivera-Ch M, Leon-Velarde F, Ghosh S, Bigham AW. Brutsaert TD, et al. Among authors: Leon-Velarde F. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24006-24011. doi: 10.1073/pnas.1906171116. Epub 2019 Nov 11. Proc Natl Acad Sci U S A. 2019. PMID: 31712437 Free PMC article.
Highland native Andeans have resided at altitude for millennia. They display high aerobic capacity (VO(2)max) at altitude, which may be a reflection of genetic adaptation to hypoxia. ...These findings contextualize previous reports of natural selection at EGLN1 in A …
Highland native Andeans have resided at altitude for millennia. They display high aerobic capacity (VO(2)max) at altitude, whi …
Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults.
Lüneburg N, Siques P, Brito J, De La Cruz JJ, León-Velarde F, Hannemann J, Ibanez C, Böger RH. Lüneburg N, et al. Among authors: Leon-Velarde F. High Alt Med Biol. 2017 Sep;18(3):226-233. doi: 10.1089/ham.2016.0123. Epub 2017 Apr 28. High Alt Med Biol. 2017. PMID: 28453332 Free PMC article.
Long-term intermittent exposure to high altitude elevates asymmetric dimethylarginine in first exposed young adults. High Alt Med Biol. 18:226-233, 2017....This may contribute to impaired NO production at altitude and may also be predictive of altitude-associ …
Long-term intermittent exposure to high altitude elevates asymmetric dimethylarginine in first exposed young adults. High Alt Med Bio …
Increased Cardiometabolic Risk and Worsening Hypoxemia at High Altitude.
Miele CH, Schwartz AR, Gilman RH, Pham L, Wise RA, Davila-Roman VG, Jun JC, Polotsky VY, Miranda JJ, Leon-Velarde F, Checkley W. Miele CH, et al. Among authors: Leon-Velarde F. High Alt Med Biol. 2016 Jun;17(2):93-100. doi: 10.1089/ham.2015.0084. High Alt Med Biol. 2016. PMID: 27281472 Free PMC article.
In high-altitude populations in Puno, Peru, a higher BMI and lower pulmonary function were associated with lower resting daytime oxyhemoglobin saturation. ...Worsening hypoxia of any degree in high-altitude dwellers may be an independent risk factor for cardiovascul …
In high-altitude populations in Puno, Peru, a higher BMI and lower pulmonary function were associated with lower resting daytime oxyh …
Obesity as a Conditioning Factor for High-Altitude Diseases.
San Martin R, Brito J, Siques P, León-Velarde F. San Martin R, et al. Among authors: Leon-Velarde F. Obes Facts. 2017;10(4):363-372. doi: 10.1159/000477461. Epub 2017 Aug 16. Obes Facts. 2017. PMID: 28810235 Free PMC article. Review.
This association could be rooted in the interactions between obesity-related metabolic alterations and critical ventilation impairments due to obesity, which would aggravate hypobaric hypoxia at high altitudes, leading to hypoxemia, which is a trigger for developing high- …
This association could be rooted in the interactions between obesity-related metabolic alterations and critical ventilation impairments due …
Noninvasive Assessment of Excessive Erythrocytosis as a Screening Method for Chronic Mountain Sickness at High Altitude.
Vyas KJ, Danz D, Gilman RH, Wise RA, León-Velarde F, Miranda JJ, Checkley W. Vyas KJ, et al. Among authors: Leon-Velarde F. High Alt Med Biol. 2015 Jun;16(2):162-8. doi: 10.1089/ham.2015.0026. Epub 2015 May 14. High Alt Med Biol. 2015. PMID: 25973777 Free PMC article.
Noninvasive assessment of excessive erythrocytosis as a screening method for chronic mountain sickness at high altitude. High Alt Med Biol 16:162-168, 2015....A noninvasive, spot-check test of total hemoglobin had low bias and high discrimination for the detection of EE in …
Noninvasive assessment of excessive erythrocytosis as a screening method for chronic mountain sickness at high altitude. High Alt Med …
Exhaled nitric oxide in ethnically diverse high-altitude native populations: A comparative study.
Ghosh S, Kiyamu M, Contreras P, León-Velarde F, Bigham A, Brutsaert TD. Ghosh S, et al. Among authors: Leon-Velarde F. Am J Phys Anthropol. 2019 Nov;170(3):451-458. doi: 10.1002/ajpa.23915. Epub 2019 Aug 9. Am J Phys Anthropol. 2019. PMID: 31396964
OBJECTIVES: Andean and Tibetan high-altitude natives exhibit a high concentration of nitric oxide (NO) in the lungs, suggesting that NO plays an adaptive role in offsetting hypobaric hypoxia. ...The latter included three distinct subgroups defined as those residing at a
OBJECTIVES: Andean and Tibetan high-altitude natives exhibit a high concentration of nitric oxide (NO) in the lungs, suggesting that …
Long-Term Intermittent Work at High Altitude: Right Heart Functional and Morphological Status and Associated Cardiometabolic Factors.
Brito J, Siques P, López R, Romero R, León-Velarde F, Flores K, Lüneburg N, Hannemann J, Böger RH. Brito J, et al. Among authors: Leon-Velarde F. Front Physiol. 2018 Mar 22;9:248. doi: 10.3389/fphys.2018.00248. eCollection 2018. Front Physiol. 2018. PMID: 29623044 Free PMC article.
Background: Living at high altitude or with chronic hypoxia implies functional and morphological changes in the right ventricle and pulmonary vasculature with a 10% prevalence of high-altitude pulmonary hypertension (HAPH). The implications of working intermittently …
Background: Living at high altitude or with chronic hypoxia implies functional and morphological changes in the right ventricle and p …
114 results
Jump to page
Feedback