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Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression.
Leonard B, Maes M. Leonard B, et al. Neurosci Biobehav Rev. 2012 Feb;36(2):764-85. doi: 10.1016/j.neubiorev.2011.12.005. Epub 2011 Dec 19. Neurosci Biobehav Rev. 2012. PMID: 22197082 Review.
The psychoneuroimmunology of depression.
Leonard BE, Myint A. Leonard BE, et al. Hum Psychopharmacol. 2009 Apr;24(3):165-75. doi: 10.1002/hup.1011. Hum Psychopharmacol. 2009. PMID: 19212943 Review.
Animal inflammation-based models of depression and their application to drug discovery.
Ma L, Demin KA, Kolesnikova TO, Khatsko SL, Zhu X, Yuan X, Song C, Meshalkina DA, Leonard BE, Tian L, Kalueff AV. Ma L, et al. Among authors: Leonard BE. Expert Opin Drug Discov. 2017 Oct;12(10):995-1009. doi: 10.1080/17460441.2017.1362385. Epub 2017 Aug 17. Expert Opin Drug Discov. 2017. PMID: 28816544 Review.
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