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Tissue plasminogen activator has an O-linked fucose attached to threonine-61 in the epidermal growth factor domain.
Harris RJ, Leonard CK, Guzzetta AW, Spellman MW. Harris RJ, et al. Among authors: leonard ck. Biochemistry. 1991 Mar 5;30(9):2311-4. doi: 10.1021/bi00223a004. Biochemistry. 1991. PMID: 1900431
The influence of carbohydrate structure on the clearance of recombinant tissue-type plasminogen activator.
Hotchkiss A, Refino CJ, Leonard CK, O'Connor JV, Crowley C, McCabe J, Tate K, Nakamura G, Powers D, Levinson A, et al. Hotchkiss A, et al. Among authors: leonard ck. Thromb Haemost. 1988 Oct 31;60(2):255-61. Thromb Haemost. 1988. PMID: 2851193
Carbohydrate structures of human tissue plasminogen activator expressed in Chinese hamster ovary cells.
Spellman MW, Basa LJ, Leonard CK, Chakel JA, O'Connor JV, Wilson S, van Halbeek H. Spellman MW, et al. Among authors: leonard ck. J Biol Chem. 1989 Aug 25;264(24):14100-11. J Biol Chem. 1989. PMID: 2503511 Free article.
Study of the primary structure of recombinant tissue plasminogen activator by reversed-phase high-performance liquid chromatographic tryptic mapping.
Chloupek RC, Harris RJ, Leonard CK, Keck RG, Keyt BA, Spellman MW, Jones AJ, Hancock WS. Chloupek RC, et al. Among authors: leonard ck. J Chromatogr. 1989 Feb 3;463(2):375-96. doi: 10.1016/s0021-9673(01)84491-5. J Chromatogr. 1989. PMID: 2496137
Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.
Leonard CK, Spellman MW, Riddle L, Harris RJ, Thomas JN, Gregory TJ. Leonard CK, et al. J Biol Chem. 1990 Jun 25;265(18):10373-82. J Biol Chem. 1990. PMID: 2355006 Free article.
Carbohydrate structures of recombinant soluble human CD4 expressed in Chinese hamster ovary cells.
Spellman MW, Leonard CK, Basa LJ, Gelineo I, van Halbeek H. Spellman MW, et al. Among authors: leonard ck. Biochemistry. 1991 Mar 5;30(9):2395-406. doi: 10.1021/bi00223a015. Biochemistry. 1991. PMID: 2001369
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