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398 results
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Enhanced extracellular matrix production and differentiation of human embryonic germ cell derivatives in biodegradable poly(epsilon-caprolactone-co-ethyl ethylene phosphate) scaffold.
Yim EK, Wen J, Leong KW. Yim EK, et al. Acta Biomater. 2006 Jul;2(4):365-76. doi: 10.1016/j.actbio.2006.03.006. Epub 2006 May 18. Acta Biomater. 2006. PMID: 16709468
A novel biodegradable gene carrier based on polyphosphoester.
Wang J, Mao HQ, Leong KW. Wang J, et al. J Am Chem Soc. 2001 Sep 26;123(38):9480-1. doi: 10.1021/ja016062m. J Am Chem Soc. 2001. PMID: 11562246 No abstract available.
A new nerve guide conduit material composed of a biodegradable poly(phosphoester).
Wang S, Wan AC, Xu X, Gao S, Mao HQ, Leong KW, Yu H. Wang S, et al. Biomaterials. 2001 May;22(10):1157-69. doi: 10.1016/s0142-9612(00)00356-2. Biomaterials. 2001. PMID: 11352095
pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities.
Zhang J, Li J, Shi Z, Yang Y, Xie X, Lee SM, Wang Y, Leong KW, Chen M. Zhang J, et al. Acta Biomater. 2017 Aug;58:349-364. doi: 10.1016/j.actbio.2017.04.029. Epub 2017 Apr 26. Acta Biomater. 2017. PMID: 28455219
Scaffold-mediated non-viral delivery platform for CRISPR/Cas9-based genome editing.
Chin JS, Chooi WH, Wang H, Ong W, Leong KW, Chew SY. Chin JS, et al. Acta Biomater. 2019 May;90:60-70. doi: 10.1016/j.actbio.2019.04.020. Epub 2019 Apr 9. Acta Biomater. 2019. PMID: 30978509
Sustained delivery of siRNA/mesoporous silica nanoparticle complexes from nanofiber scaffolds for long-term gene silencing.
Pinese C, Lin J, Milbreta U, Li M, Wang Y, Leong KW, Chew SY. Pinese C, et al. Acta Biomater. 2018 Aug;76:164-177. doi: 10.1016/j.actbio.2018.05.054. Epub 2018 Jun 15. Acta Biomater. 2018. PMID: 29890267
Mitigation of hypertrophic scar contraction via an elastomeric biodegradable scaffold.
Lorden ER, Miller KJ, Bashirov L, Ibrahim MM, Hammett E, Jung Y, Medina MA, Rastegarpour A, Selim MA, Leong KW, Levinson H. Lorden ER, et al. Biomaterials. 2015 Mar;43:61-70. doi: 10.1016/j.biomaterials.2014.12.003. Epub 2015 Jan 7. Biomaterials. 2015. PMID: 25591962
Multifunctional nanorods for gene delivery.
Salem AK, Searson PC, Leong KW. Salem AK, et al. Nat Mater. 2003 Oct;2(10):668-71. doi: 10.1038/nmat974. Epub 2003 Sep 14. Nat Mater. 2003. PMID: 12970757
Radio-responsive gene therapy for malignant glioma cells without the radiosensitive promoter: Caspase-3 gene therapy combined with radiation.
Tsurushima H, Yuan X, Dillehay LE, Leong KW. Tsurushima H, et al. Cancer Lett. 2007 Feb 8;246(1-2):318-23. doi: 10.1016/j.canlet.2006.03.015. Epub 2006 Apr 27. Cancer Lett. 2007. PMID: 16644107
Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells.
Yim EK, Darling EM, Kulangara K, Guilak F, Leong KW. Yim EK, et al. Biomaterials. 2010 Feb;31(6):1299-306. doi: 10.1016/j.biomaterials.2009.10.037. Epub 2009 Oct 30. Biomaterials. 2010. PMID: 19879643 Free PMC article.
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