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Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML.
Kempf JM, Weser S, Bartoschek MD, Metzeler KH, Vick B, Herold T, Völse K, Mattes R, Scholz M, Wange LE, Festini M, Ugur E, Roas M, Weigert O, Bultmann S, Leonhardt H, Schotta G, Hiddemann W, Jeremias I, Spiekermann K. Kempf JM, et al. Among authors: leonhardt h. Sci Rep. 2021 Mar 12;11(1):5838. doi: 10.1038/s41598-021-84708-6. Sci Rep. 2021. PMID: 33712646 Free PMC article.
Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia.
Konstandin N, Bultmann S, Szwagierczak A, Dufour A, Ksienzyk B, Schneider F, Herold T, Mulaw M, Kakadia PM, Schneider S, Spiekermann K, Leonhardt H, Bohlander SK. Konstandin N, et al. Among authors: leonhardt h. Leukemia. 2011 Oct;25(10):1649-52. doi: 10.1038/leu.2011.134. Epub 2011 May 31. Leukemia. 2011. PMID: 21625234 No abstract available.
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain.
Frauer C, Hoffmann T, Bultmann S, Casa V, Cardoso MC, Antes I, Leonhardt H. Frauer C, et al. Among authors: leonhardt h. PLoS One. 2011;6(6):e21306. doi: 10.1371/journal.pone.0021306. Epub 2011 Jun 22. PLoS One. 2011. PMID: 21731699 Free PMC article.
CENP-C facilitates the recruitment of M18BP1 to centromeric chromatin.
Dambacher S, Deng W, Hahn M, Sadic D, Fröhlich J, Nuber A, Hoischen C, Diekmann S, Leonhardt H, Schotta G. Dambacher S, et al. Among authors: leonhardt h. Nucleus. 2012 Jan-Feb;3(1):101-10. doi: 10.4161/nucl.18955. Nucleus. 2012. PMID: 22540025 Free PMC article.
522 results