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Depletion of Mannose Receptor-Positive Tumor-associated Macrophages via a Peptide-targeted Star-shaped Polyglutamate Inhibits Breast Cancer Progression in Mice.
Lepland A, Malfanti A, Haljasorg U, Asciutto EK, Pickholz M, Bringas M, Đorđević S, Salumäe L, Peterson P, Teesalu T, Vicent MJ, Scodeller P. Lepland A, et al. Cancer Res Commun. 2022 Jun 28;2(6):533-551. doi: 10.1158/2767-9764.CRC-22-0043. eCollection 2022 Jun. Cancer Res Commun. 2022. PMID: 36923553 Free PMC article.
Peptide-guided resiquimod-loaded lignin nanoparticles convert tumor-associated macrophages from M2 to M1 phenotype for enhanced chemotherapy.
Figueiredo P, Lepland A, Scodeller P, Fontana F, Torrieri G, Tiboni M, Shahbazi MA, Casettari L, Kostiainen MA, Hirvonen J, Teesalu T, Santos HA. Figueiredo P, et al. Among authors: lepland a. Acta Biomater. 2021 Oct 1;133:231-243. doi: 10.1016/j.actbio.2020.09.038. Epub 2020 Oct 2. Acta Biomater. 2021. PMID: 33011297
Decreased Virulence of Ross River Virus Harboring a Mutation in the First Cleavage Site of Nonstructural Polyprotein Is Caused by a Novel Mechanism Leading to Increased Production of Interferon-Inducing RNAs.
Liu X, Mutso M, Utt A, Lepland A, Herrero LJ, Taylor A, Bettadapura J, Rudd PA, Merits A, Mahalingam S. Liu X, et al. Among authors: lepland a. mBio. 2018 Aug 21;9(4):e00044-18. doi: 10.1128/mBio.00044-18. mBio. 2018. PMID: 30131356 Free PMC article.