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Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1.
Deltour S, Pinte S, Guérardel C, Leprince D. Deltour S, et al. Among authors: leprince d. Biochem Biophys Res Commun. 2001 Sep 21;287(2):427-34. doi: 10.1006/bbrc.2001.5624. Biochem Biophys Res Commun. 2001. PMID: 11554746
Arginine 469 is a pivotal residue for the Hsc70-GlcNAc-binding property.
Guinez C, Mir AM, Martin N, Leprince D, Michalski JC, Vergoten G, Lefebvre T. Guinez C, et al. Among authors: leprince d. Biochem Biophys Res Commun. 2010 Oct 1;400(4):537-42. doi: 10.1016/j.bbrc.2010.08.089. Epub 2010 Sep 17. Biochem Biophys Res Commun. 2010. PMID: 20804732
Functional characterization of human Polycomb-like 3 isoforms identifies them as components of distinct EZH2 protein complexes.
Boulay G, Rosnoblet C, Guérardel C, Angrand PO, Leprince D. Boulay G, et al. Among authors: leprince d. Biochem J. 2011 Mar 1;434(2):333-42. doi: 10.1042/BJ20100944. Biochem J. 2011. PMID: 21143197
HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs).
Paget S, Dubuissez M, Dehennaut V, Nassour J, Harmon BT, Spruyt N, Loison I, Abbadie C, Rood BR, Leprince D. Paget S, et al. Among authors: leprince d. Oncotarget. 2017 Jan 10;8(2):2916-2935. doi: 10.18632/oncotarget.13807. Oncotarget. 2017. PMID: 27935866 Free PMC article.
[Chromosome arm 17p13.3: could HIC1 be the one ?].
Chopin V, Leprince D. Chopin V, et al. Among authors: leprince d. Med Sci (Paris). 2006 Jan;22(1):54-61. doi: 10.1051/medsci/200622154. Med Sci (Paris). 2006. PMID: 16386221 Review. French.
HIC1 interacts with and modulates the activity of STAT3.
Lin YM, Wang CM, Jeng JC, Leprince D, Shih HM. Lin YM, et al. Among authors: leprince d. Cell Cycle. 2013 Jul 15;12(14):2266-76. doi: 10.4161/cc.25365. Cell Cycle. 2013. PMID: 24067369 Free PMC article.
Generation of two modified mouse alleles of the Hic1 tumor suppressor gene.
Pospichalova V, Tureckova J, Fafilek B, Vojtechova M, Krausova M, Lukas J, Sloncova E, Takacova S, Divoky V, Leprince D, Plachy J, Korinek V. Pospichalova V, et al. Among authors: leprince d. Genesis. 2011 Mar;49(3):142-51. doi: 10.1002/dvg.20719. Genesis. 2011. PMID: 21309068
The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1.
Jenal M, Trinh E, Britschgi C, Britschgi A, Roh V, Vorburger SA, Tobler A, Leprince D, Fey MF, Helin K, Tschan MP. Jenal M, et al. Among authors: leprince d. Mol Cancer Res. 2009 Jun;7(6):916-22. doi: 10.1158/1541-7786.MCR-08-0359. Epub 2009 Jun 2. Mol Cancer Res. 2009. PMID: 19491197
An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity.
Stankovic-Valentin N, Deltour S, Seeler J, Pinte S, Vergoten G, Guérardel C, Dejean A, Leprince D. Stankovic-Valentin N, et al. Among authors: leprince d. Mol Cell Biol. 2007 Apr;27(7):2661-75. doi: 10.1128/MCB.01098-06. Epub 2007 Feb 5. Mol Cell Biol. 2007. PMID: 17283066 Free PMC article.
HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage-Associated Tumorigenesis.
Janeckova L, Pospichalova V, Fafilek B, Vojtechova M, Tureckova J, Dobes J, Dubuissez M, Leprince D, Baloghova N, Horazna M, Hlavata A, Stancikova J, Sloncova E, Galuskova K, Strnad H, Korinek V. Janeckova L, et al. Among authors: leprince d. Mol Cancer Res. 2015 Jul;13(7):1139-48. doi: 10.1158/1541-7786.MCR-15-0033. Epub 2015 May 1. Mol Cancer Res. 2015. PMID: 25934696 Free article.
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