Lerner RA - Search Results

1

Cofactor-containing antibodies: crystal structure of the original yellow antibody.

Zhu X, Wentworth P Jr, Kyle RA, Lerner RA, Wilson IA. Zhu X, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3581-5. doi: 10.1073/pnas.0600251103. Epub 2006 Feb 28. Proc Natl Acad Sci U S A. 2006. PMID: 16537445 Free PMC article.

2

Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens.

Wentworth P Jr, Wentworth AD, Zhu X, Wilson IA, Janda KD, Eschenmoser A, Lerner RA. Wentworth P Jr, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1490-3. doi: 10.1073/pnas.0437831100. Epub 2003 Feb 7. Proc Natl Acad Sci U S A. 2003. PMID: 12576548 Free PMC article.

3

Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.

Zhu X, Wentworth P Jr, Wentworth AD, Eschenmoser A, Lerner RA, Wilson IA. Zhu X, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2247-52. doi: 10.1073/pnas.0307311101. Proc Natl Acad Sci U S A. 2004. PMID: 14982995 Free PMC article.

4

The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis.

Zhu X, Tanaka F, Hu Y, Heine A, Fuller R, Zhong G, Olson AJ, Lerner RA, Barbas CF 3rd, Wilson IA. Zhu X, et al. Among authors: lerner ra. J Mol Biol. 2004 Nov 5;343(5):1269-80. doi: 10.1016/j.jmb.2004.08.102. J Mol Biol. 2004. PMID: 15491612

5

Selection of antibodies that regulate phenotype from intracellular combinatorial antibody libraries.

Zhang H, Wilson IA, Lerner RA. Zhang H, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15728-33. doi: 10.1073/pnas.1214275109. Epub 2012 Sep 10. Proc Natl Acad Sci U S A. 2012. PMID: 23019357 Free PMC article.

6

Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task.

Karlstrom A, Zhong G, Rader C, Larsen NA, Heine A, Fuller R, List B, Tanaka F, Wilson IA, Barbas CF 3rd, Lerner RA. Karlstrom A, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):3878-83. doi: 10.1073/pnas.97.8.3878. Proc Natl Acad Sci U S A. 2000. PMID: 10760259 Free PMC article.

7

Antibodies have the intrinsic capacity to destroy antigens.

Wentworth AD, Jones LH, Wentworth P Jr, Janda KD, Lerner RA. Wentworth AD, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10930-5. doi: 10.1073/pnas.97.20.10930. Proc Natl Acad Sci U S A. 2000. PMID: 11005865 Free PMC article.

8

Crystal structure of a bacterial cocaine esterase.

Larsen NA, Turner JM, Stevens J, Rosser SJ, Basran A, Lerner RA, Bruce NC, Wilson IA. Larsen NA, et al. Among authors: lerner ra. Nat Struct Biol. 2002 Jan;9(1):17-21. doi: 10.1038/nsb742. Nat Struct Biol. 2002. PMID: 11742345

9

A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy.

Rader C, Turner JM, Heine A, Shabat D, Sinha SC, Wilson IA, Lerner RA, Barbas CF. Rader C, et al. Among authors: lerner ra. J Mol Biol. 2003 Sep 26;332(4):889-99. doi: 10.1016/s0022-2836(03)00992-6. J Mol Biol. 2003. PMID: 12972259

10

Metabolite-initiated protein misfolding may trigger Alzheimer's disease.

Zhang Q, Powers ET, Nieva J, Huff ME, Dendle MA, Bieschke J, Glabe CG, Eschenmoser A, Wentworth P Jr, Lerner RA, Kelly JW. Zhang Q, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4752-7. doi: 10.1073/pnas.0400924101. Epub 2004 Mar 19. Proc Natl Acad Sci U S A. 2004. PMID: 15034169 Free PMC article.

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