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An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.
Phillips B, Veljkovic E, Boué S, Schlage WK, Vuillaume G, Martin F, Titz B, Leroy P, Buettner A, Elamin A, Oviedo A, Cabanski M, De León H, Guedj E, Schneider T, Talikka M, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J. Phillips B, et al. Among authors: leroy p. Toxicol Sci. 2016 Feb;149(2):411-32. doi: 10.1093/toxsci/kfv243. Epub 2015 Nov 25. Toxicol Sci. 2016. PMID: 26609137 Free PMC article.
Systems toxicology meta-analysis of in vitro assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract.
Iskandar AR, Titz B, Sewer A, Leroy P, Schneider T, Zanetti F, Mathis C, Elamin A, Frentzel S, Schlage WK, Martin F, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: leroy p. Toxicol Res (Camb). 2017 May 29;6(5):631-653. doi: 10.1039/c7tx00047b. eCollection 2017 Sep 1. Toxicol Res (Camb). 2017. PMID: 30090531 Free PMC article.
A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes.
Kogel U, Schlage WK, Martin F, Xiang Y, Ansari S, Leroy P, Vanscheeuwijck P, Gebel S, Buettner A, Wyss C, Esposito M, Hoeng J, Peitsch MC. Kogel U, et al. Among authors: leroy p. Food Chem Toxicol. 2014 Jun;68:204-17. doi: 10.1016/j.fct.2014.02.034. Epub 2014 Mar 12. Food Chem Toxicol. 2014. PMID: 24632068 Free article.
Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts.
Iskandar AR, Xiang Y, Frentzel S, Talikka M, Leroy P, Kuehn D, Guedj E, Martin F, Mathis C, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: leroy p. Toxicol Sci. 2015 Sep;147(1):207-21. doi: 10.1093/toxsci/kfv122. Epub 2015 Jun 16. Toxicol Sci. 2015. PMID: 26085348 Free PMC article.
Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe-/- Mice-An Integrative Systems Toxicology Analysis.
Titz B, Boué S, Phillips B, Talikka M, Vihervaara T, Schneider T, Nury C, Elamin A, Guedj E, Peck MJ, Schlage WK, Cabanski M, Leroy P, Vuillaume G, Martin F, Ivanov NV, Veljkovic E, Ekroos K, Laaksonen R, Vanscheeuwijck P, Peitsch MC, Hoeng J. Titz B, et al. Among authors: leroy p. Toxicol Sci. 2016 Feb;149(2):441-57. doi: 10.1093/toxsci/kfv244. Epub 2015 Nov 17. Toxicol Sci. 2016. PMID: 26582801 Free PMC article.
Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice.
Ansari S, Baumer K, Boué S, Dijon S, Dulize R, Ekroos K, Elamin A, Foong C, Guedj E, Hoeng J, Ivanov NV, Krishnan S, Leroy P, Martin F, Merg C, Peck MJ, Peitsch MC, Phillips B, Schlage WK, Schneider T, Talikka M, Titz B, Vanscheeuwijck P, Veljkovic E, Vihervaara T, Vuillaume G, Woon CQ. Ansari S, et al. Among authors: leroy p. Sci Data. 2016 Jan 5;3:150077. doi: 10.1038/sdata.2015.77. Sci Data. 2016. PMID: 26731301 Free PMC article.
Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe -/- mice--a systems toxicology analysis.
Lo Sasso G, Titz B, Nury C, Boué S, Phillips B, Belcastro V, Schneider T, Dijon S, Baumer K, Peric D, Dulize R, Elamin A, Guedj E, Buettner A, Leroy P, Kleinhans S, Vuillaume G, Veljkovic E, Ivanov NV, Martin F, Vanscheeuwijck P, Peitsch MC, Hoeng J. Lo Sasso G, et al. Among authors: leroy p. Inhal Toxicol. 2016 Apr;28(5):226-40. doi: 10.3109/08958378.2016.1150368. Epub 2016 Mar 30. Inhal Toxicol. 2016. PMID: 27027324
An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.
Phillips B, Veljkovic E, Boué S, Schlage WK, Vuillaume G, Martin F, Titz B, Leroy P, Buettner A, Elamin A, Oviedo A, Cabanski M, De León H, Guedj E, Schneider T, Talikka M, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J. Phillips B, et al. Among authors: leroy p. Toxicol Sci. 2016 Jun;151(2):462-4. doi: 10.1093/toxsci/kfw062. Toxicol Sci. 2016. PMID: 27225756 Free PMC article. No abstract available.
Systems Toxicology Assessment of the Biological Impact of a Candidate Modified Risk Tobacco Product on Human Organotypic Oral Epithelial Cultures.
Zanetti F, Sewer A, Mathis C, Iskandar AR, Kostadinova R, Schlage WK, Leroy P, Majeed S, Guedj E, Trivedi K, Martin F, Elamin A, Merg C, Ivanov NV, Frentzel S, Peitsch MC, Hoeng J. Zanetti F, et al. Among authors: leroy p. Chem Res Toxicol. 2016 Aug 15;29(8):1252-69. doi: 10.1021/acs.chemrestox.6b00174. Epub 2016 Aug 5. Chem Res Toxicol. 2016. PMID: 27404394
537 results