Lesko L - Search Results

1

Efficacy of flibanserin in women with hypoactive sexual desire disorder: results from the BEGONIA trial.

Katz M, DeRogatis LR, Ackerman R, Hedges P, Lesko L, Garcia M Jr, Sand M; BEGONIA trial investigators. Katz M, et al. Among authors: lesko l. J Sex Med. 2013 Jul;10(7):1807-15. doi: 10.1111/jsm.12189. Epub 2013 May 14. J Sex Med. 2013. PMID: 23672269 Clinical Trial.

2

Treatment of hypoactive sexual desire disorder in premenopausal women: efficacy of flibanserin in the DAISY study.

Thorp J, Simon J, Dattani D, Taylor L, Kimura T, Garcia M Jr, Lesko L, Pyke R; DAISY trial investigators. Thorp J, et al. Among authors: lesko l. J Sex Med. 2012 Mar;9(3):793-804. doi: 10.1111/j.1743-6109.2011.02595.x. Epub 2012 Jan 12. J Sex Med. 2012. PMID: 22239862 Clinical Trial.

3

Open-label extension study of flibanserin in women with hypoactive sexual desire disorder.

Jayne C, Simon JA, Taylor LV, Kimura T, Lesko LM; SUNFLOWER study investigators. Jayne C, et al. J Sex Med. 2012 Dec;9(12):3180-8. doi: 10.1111/j.1743-6109.2012.02942.x. Epub 2012 Oct 11. J Sex Med. 2012. PMID: 23057791 Clinical Trial.

4

Exploring the impact of CYP2D6 and UGT2B7 gene-drug interactions, and CYP-mediated DDI on oxycodone and oxymorphone pharmacokinetics using physiologically-based pharmacokinetic modeling and simulation.

Klose M, Cristofoletti R, Silva CM, Mangal N, Turgeon J, Michaud V, Lesko LJ, Schmidt S. Klose M, et al. Among authors: lesko lj. Eur J Pharm Sci. 2024 Mar 1;194:106689. doi: 10.1016/j.ejps.2023.106689. Epub 2024 Jan 1. Eur J Pharm Sci. 2024. PMID: 38171419 Free article.

5

Identification of Novel and Early Biomarkers for Cisplatin-induced Nephrotoxicity and the Nephroprotective Role of Cimetidine using a Pharmacometabolomic-based Approach Coupled with In Vitro Toxicodynamic Modeling and Simulation.

Mody H, Nair S, Rump A, Vaidya TR, Garrett TJ, Lesko L, Ait-Oudhia S. Mody H, et al. Among authors: lesko l. J Pharm Sci. 2024 Jan;113(1):268-277. doi: 10.1016/j.xphs.2023.11.018. Epub 2023 Nov 20. J Pharm Sci. 2024. PMID: 37992870 Free article.

6

Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of Cisplatin.

Mody H, Vaidya TR, Lesko LJ, Ait-Oudhia S. Mody H, et al. Among authors: lesko lj. Cells. 2022 Dec 23;12(1):57. doi: 10.3390/cells12010057. Cells. 2022. PMID: 36611850 Free PMC article.

7

Fabrication and In Vitro Characterization of Novel Hydroxyapatite Scaffolds 3D Printed Using Polyvinyl Alcohol as a Thermoplastic Binder.

Thurzo A, Gálfiová P, Nováková ZV, Polák Š, Varga I, Strunga M, Urban R, Surovková J, Leško Ľ, Hajdúchová Z, Feranc J, Janek M, Danišovič Ľ. Thurzo A, et al. Among authors: lesko l. Int J Mol Sci. 2022 Nov 28;23(23):14870. doi: 10.3390/ijms232314870. Int J Mol Sci. 2022. PMID: 36499194 Free PMC article.

8

Application of a patient-centered reverse translational systems-based approach to understand mechanisms of an adverse drug reaction of immune checkpoint inhibitors.

Kim S, Lahu G, Vakilynejad M, Soldatos TG, Jackson DB, Lesko LJ, Trame MN. Kim S, et al. Among authors: lesko lj. Clin Transl Sci. 2022 Jun;15(6):1430-1438. doi: 10.1111/cts.13254. Epub 2022 Mar 5. Clin Transl Sci. 2022. PMID: 35191192 Free PMC article.

9

Advancing drug safety science by integrating molecular knowledge with post-marketing adverse event reports.

Soldatos TG, Kim S, Schmidt S, Lesko LJ, Jackson DB. Soldatos TG, et al. Among authors: lesko lj. CPT Pharmacometrics Syst Pharmacol. 2022 May;11(5):540-555. doi: 10.1002/psp4.12765. Epub 2022 Feb 20. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35143713 Free PMC article. Review.

10

A case study of a patient-centered reverse translational systems-based approach to understand adverse event profiles in drug development.

Kim S, Lahu G, Vakilynejad M, Soldatos TG, Jackson DB, Lesko LJ, Trame MN. Kim S, et al. Among authors: lesko lj. Clin Transl Sci. 2022 Apr;15(4):1003-1013. doi: 10.1111/cts.13219. Epub 2022 Jan 11. Clin Transl Sci. 2022. PMID: 35014203 Free PMC article.

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