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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.
Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, Vega F, Yu N, Wang J, Singh K, Zonin F, Vaisberg E, Churakova T, Liu M, Gorman D, Wagner J, Zurawski S, Liu Y, Abrams JS, Moore KW, Rennick D, de Waal-Malefyt R, Hannum C, Bazan JF, Kastelein RA. Oppmann B, et al. Among authors: lesley r. Immunity. 2000 Nov;13(5):715-25. doi: 10.1016/s1074-7613(00)00070-4. Immunity. 2000. PMID: 11114383 Free article.
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo.
Fort MM, Cheung J, Yen D, Li J, Zurawski SM, Lo S, Menon S, Clifford T, Hunte B, Lesley R, Muchamuel T, Hurst SD, Zurawski G, Leach MW, Gorman DM, Rennick DM. Fort MM, et al. Among authors: lesley r. Immunity. 2001 Dec;15(6):985-95. doi: 10.1016/s1074-7613(01)00243-6. Immunity. 2001. PMID: 11754819 Free article.
Anti-B-Cell Maturation Antigen BiTE Molecule AMG 420 Induces Responses in Multiple Myeloma.
Topp MS, Duell J, Zugmaier G, Attal M, Moreau P, Langer C, Krönke J, Facon T, Salnikov AV, Lesley R, Beutner K, Kalabus J, Rasmussen E, Riemann K, Minella AC, Munzert G, Einsele H. Topp MS, et al. Among authors: lesley r. J Clin Oncol. 2020 Mar 10;38(8):775-783. doi: 10.1200/JCO.19.02657. Epub 2020 Jan 2. J Clin Oncol. 2020. PMID: 31895611 Clinical Trial.
Development, reliability, validity, and acceptability of the remote administration of the Edinburgh Cognitive and Behavioural ALS Screen (ECAS).
Gray D, Lesley R, Mayberry EJ, Williams L, McHutchison C, Newton J, Pal S, Chandran S, MacPherson SE, Abrahams S; MND Consortium. Gray D, et al. Among authors: lesley r. Amyotroph Lateral Scler Frontotemporal Degener. 2024 Feb;25(1-2):96-103. doi: 10.1080/21678421.2023.2278512. Epub 2024 Jan 23. Amyotroph Lateral Scler Frontotemporal Degener. 2024. PMID: 37950613
15 results