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Role of HLA Adaptation in HIV Evolution.
Kløverpris HN, Leslie A, Goulder P. Kløverpris HN, et al. Among authors: leslie a. Front Immunol. 2016 Jan 18;6:665. doi: 10.3389/fimmu.2015.00665. eCollection 2015. Front Immunol. 2016. PMID: 26834742 Free PMC article. Review.
HIV evolution: CTL escape mutation and reversion after transmission.
Leslie AJ, Pfafferott KJ, Chetty P, Draenert R, Addo MM, Feeney M, Tang Y, Holmes EC, Allen T, Prado JG, Altfeld M, Brander C, Dixon C, Ramduth D, Jeena P, Thomas SA, St John A, Roach TA, Kupfer B, Luzzi G, Edwards A, Taylor G, Lyall H, Tudor-Williams G, Novelli V, Martinez-Picado J, Kiepiela P, Walker BD, Goulder PJ. Leslie AJ, et al. Nat Med. 2004 Mar;10(3):282-9. doi: 10.1038/nm992. Epub 2004 Feb 8. Nat Med. 2004. PMID: 14770175
Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection.
Draenert R, Le Gall S, Pfafferott KJ, Leslie AJ, Chetty P, Brander C, Holmes EC, Chang SC, Feeney ME, Addo MM, Ruiz L, Ramduth D, Jeena P, Altfeld M, Thomas S, Tang Y, Verrill CL, Dixon C, Prado JG, Kiepiela P, Martinez-Picado J, Walker BD, Goulder PJ. Draenert R, et al. J Exp Med. 2004 Apr 5;199(7):905-15. doi: 10.1084/jem.20031982. J Exp Med. 2004. PMID: 15067030 Free PMC article.
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.
Kiepiela P, Leslie AJ, Honeyborne I, Ramduth D, Thobakgale C, Chetty S, Rathnavalu P, Moore C, Pfafferott KJ, Hilton L, Zimbwa P, Moore S, Allen T, Brander C, Addo MM, Altfeld M, James I, Mallal S, Bunce M, Barber LD, Szinger J, Day C, Klenerman P, Mullins J, Korber B, Coovadia HM, Walker BD, Goulder PJ. Kiepiela P, et al. Nature. 2004 Dec 9;432(7018):769-75. doi: 10.1038/nature03113. Nature. 2004. PMID: 15592417
Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.
Leslie A, Kavanagh D, Honeyborne I, Pfafferott K, Edwards C, Pillay T, Hilton L, Thobakgale C, Ramduth D, Draenert R, Le Gall S, Luzzi G, Edwards A, Brander C, Sewell AK, Moore S, Mullins J, Moore C, Mallal S, Bhardwaj N, Yusim K, Phillips R, Klenerman P, Korber B, Kiepiela P, Walker B, Goulder P. Leslie A, et al. J Exp Med. 2005 Mar 21;201(6):891-902. doi: 10.1084/jem.20041455. J Exp Med. 2005. PMID: 15781581 Free PMC article.
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1.
Martinez-Picado J, Prado JG, Fry EE, Pfafferott K, Leslie A, Chetty S, Thobakgale C, Honeyborne I, Crawford H, Matthews P, Pillay T, Rousseau C, Mullins JI, Brander C, Walker BD, Stuart DI, Kiepiela P, Goulder P. Martinez-Picado J, et al. Among authors: leslie a. J Virol. 2006 Apr;80(7):3617-23. doi: 10.1128/JVI.80.7.3617-3623.2006. J Virol. 2006. PMID: 16537629 Free PMC article.
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. Day CL, et al. Among authors: leslie aj. Nature. 2006 Sep 21;443(7109):350-4. doi: 10.1038/nature05115. Epub 2006 Aug 20. Nature. 2006. PMID: 16921384
Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.
Leslie A, Price DA, Mkhize P, Bishop K, Rathod A, Day C, Crawford H, Honeyborne I, Asher TE, Luzzi G, Edwards A, Rousseau CM, Mullins JI, Tudor-Williams G, Novelli V, Brander C, Douek DC, Kiepiela P, Walker BD, Goulder PJ. Leslie A, et al. J Immunol. 2006 Oct 1;177(7):4699-708. doi: 10.4049/jimmunol.177.7.4699. J Immunol. 2006. PMID: 16982909
472 results