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Vaccination of a melanoma patient with mature dendritic cells pulsed with MAGE-3 peptides triggers the activity of nonvaccine anti-tumor cells.
Carrasco J, Van Pel A, Neyns B, Lethé B, Brasseur F, Renkvist N, van der Bruggen P, van Baren N, Paulus R, Thielemans K, Boon T, Godelaine D. Carrasco J, et al. Among authors: lethe b. J Immunol. 2008 Mar 1;180(5):3585-93. doi: 10.4049/jimmunol.180.5.3585. J Immunol. 2008. PMID: 18292586 Free article. Clinical Trial.
Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma.
Kruit WH, van Ojik HH, Brichard VG, Escudier B, Dorval T, Dréno B, Patel P, van Baren N, Avril MF, Piperno S, Khammari A, Stas M, Ritter G, Lethé B, Godelaine D, Brasseur F, Zhang Y, van der Bruggen P, Boon T, Eggermont AM, Marchand M. Kruit WH, et al. Among authors: lethe b. Int J Cancer. 2005 Nov 20;117(4):596-604. doi: 10.1002/ijc.21264. Int J Cancer. 2005. PMID: 15945101 Free article. Clinical Trial.
Local immunostimulation leading to rejection of accepted male skin grafts by female mice as a model for cancer immunotherapy.
Bourdeaux C, Lurquin C, Jacquemart I, Lethé B, Brasseur F, van Baren N, Baurain JF, Dyson J, Van Snick J, Uyttenhove C, Boon T. Bourdeaux C, et al. Among authors: lethe b. Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3502-7. doi: 10.1073/pnas.1401115111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550491 Free PMC article.
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