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Etanercept for the treatment of rheumatoid arthritis.
Lethaby A, Lopez-Olivo MA, Maxwell L, Burls A, Tugwell P, Wells GA. Lethaby A, et al. Cochrane Database Syst Rev. 2013 May 31;(5):CD004525. doi: 10.1002/14651858.CD004525.pub2. Cochrane Database Syst Rev. 2013. PMID: 23728649 Review.
SELECTION CRITERIA: All controlled trials (minimum 24 weeks' duration) comparing four possible combinations: 1) etanercept (10 mg or 25 mg twice weekly) plus a traditional DMARD (either MTX or sulphasalazine) versus a DMARD, 2) etanercept plus DMARD versus etanercep …
SELECTION CRITERIA: All controlled trials (minimum 24 weeks' duration) comparing four possible combinations: 1) etanercept (10 mg or 25 mg t …
Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding.
Lethaby A, Shepperd S, Cooke I, Farquhar C. Lethaby A, et al. Cochrane Database Syst Rev. 2000;(2):CD000329. doi: 10.1002/14651858.CD000329. Cochrane Database Syst Rev. 2000. PMID: 10796528 Updated. Review.
The benefits claimed for these therapies are reduced trauma and post-operative complications to the woman, reduced need for a general anaesthetic, direct cost savings to the health service due largely to a shift from inpatient to day case treatment and indirect cost …
The benefits claimed for these therapies are reduced trauma and post-operative complications to the woman, reduced need for a general …
Cyclical progestogens for heavy menstrual bleeding.
Lethaby A, Irvine G, Cameron I. Lethaby A, et al. Cochrane Database Syst Rev. 2000;(2):CD001016. doi: 10.1002/14651858.CD001016. Cochrane Database Syst Rev. 2000. PMID: 10796587 Updated. Review.
OBJECTIVES: The primary objective of this review is to investigate the effectiveness of oral progestogen therapy taken either during the luteal phase or for a longer course of 21 days in achieving a reduction in menstrual blood loss in women of reproductive years wi …
OBJECTIVES: The primary objective of this review is to investigate the effectiveness of oral progestogen therapy taken either during the lut …
Nonsteroidal anti-inflammatory drugs for heavy menstrual bleeding.
Lethaby A, Augood C, Duckitt K. Lethaby A, et al. Cochrane Database Syst Rev. 2000;(2):CD000400. doi: 10.1002/14651858.CD000400. Cochrane Database Syst Rev. 2000. PMID: 10796714 Updated. Review.
Although surgery is often used as a treatment, a range of medical therapies are also available. Nonsteroidal anti-inflammatory drugs or prostaglandin synthetase inhibitors reduce prostaglandin levels which are elevated in women with excessive menstrual bleeding and …
Although surgery is often used as a treatment, a range of medical therapies are also available. Nonsteroidal anti-inflammatory …
Hormone replacement therapy in postmenopausal women: endometrial hyperplasia and irregular bleeding.
Lethaby A, Farquhar C, Sarkis A, Roberts H, Jepson R, Barlow D. Lethaby A, et al. Cochrane Database Syst Rev. 2000;(2):CD000402. doi: 10.1002/14651858.CD000402. Cochrane Database Syst Rev. 2000. PMID: 10796715 Updated. Review.
Irregular bleeding, however, was more likely under a continuous than a sequential oestrogen-progestogen regimen (OR = 2.3, 95% CI 2.1-2.5) but at longer duration of treatment, continuous therapy was more protective than sequential therapy in preventing endometrial h …
Irregular bleeding, however, was more likely under a continuous than a sequential oestrogen-progestogen regimen (OR = 2.3, 95% …
Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids.
Lethaby A, Vollenhoven B, Sowter M. Lethaby A, et al. Cochrane Database Syst Rev. 2000;(2):CD000547. doi: 10.1002/14651858.CD000547. Cochrane Database Syst Rev. 2000. PMID: 10796723 Updated. Review.
Fibroid growth is stimulated by oestrogen and gonadotropin releasing hormone agonists (GnRHa) which induce a state of hypoestrogenism have been investigated as a potential treatment. ...For patients undergoing hysterectomy, a vaginal procedure is more like...
Fibroid growth is stimulated by oestrogen and gonadotropin releasing hormone agonists (GnRHa) which induce a state of hypoestrogenism …
Progesterone/progestogen releasing intrauterine systems versus either placebo or any other medication for heavy menstrual bleeding.
Lethaby AE, Cooke I, Rees M. Lethaby AE, et al. Cochrane Database Syst Rev. 2000;(2):CD002126. doi: 10.1002/14651858.CD002126. Cochrane Database Syst Rev. 2000. PMID: 10796865 Updated. Review.
Hysterectomy is often used to treat women with this complaint but medical therapy may be a successful alternative. The intrauterine coil device was originally developed as a contraceptive but the addition of uterine relaxing hormones, or progestogens, to these devic …
Hysterectomy is often used to treat women with this complaint but medical therapy may be a successful alternative. The intrauterine c …
Antifibrinolytics for heavy menstrual bleeding.
Lethaby A, Farquhar C, Cooke I. Lethaby A, et al. Cochrane Database Syst Rev. 2000;(4):CD000249. doi: 10.1002/14651858.CD000249. Cochrane Database Syst Rev. 2000. PMID: 11034679 Updated. Review.
Plasminogen activator inhibitors (antifibrinolytic agents) have therefore been promoted as a treatment for heavy menstrual bleeding. ...The remaining three trials had a crossover design and despite contacting the authors and appropriate companies, we were unable to …
Plasminogen activator inhibitors (antifibrinolytic agents) have therefore been promoted as a treatment for heavy menstrual bleeding. …
Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids.
Lethaby A, Vollenhoven B, Sowter M. Lethaby A, et al. Cochrane Database Syst Rev. 2001;(2):CD000547. doi: 10.1002/14651858.CD000547. Cochrane Database Syst Rev. 2001. PMID: 11405968 Updated. Review.
Fibroid growth is stimulated by oestrogen and gonadotropin releasing hormone agonists (GnRHa) which induce a state of hypoestrogenism have been investigated as a potential treatment. ...Hysterectomy appeared to be easier after pre-treatment with GnRH analogue therap …
Fibroid growth is stimulated by oestrogen and gonadotropin releasing hormone agonists (GnRHa) which induce a state of hypoestrogenism …
Nonsteroidal anti-inflammatory drugs for heavy menstrual bleeding.
Lethaby A, Augood C, Duckitt K. Lethaby A, et al. Cochrane Database Syst Rev. 2002;(1):CD000400. doi: 10.1002/14651858.CD000400. Cochrane Database Syst Rev. 2002. PMID: 11869575 Updated. Review.
Although surgery is often used as a treatment, a range of medical therapies are also available. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels which are elevated in women with excessive menstrual bleeding and also may have a beneficial effec …
Although surgery is often used as a treatment, a range of medical therapies are also available. Nonsteroidal anti-inflammatory …
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