Leung AKL - Search Results

1

ADP-ribosyltransferases, an update on function and nomenclature.

Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagné JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehtiö L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawłowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Yélamos J, Yu X, Zaja R, Ziegler M. Lüscher B, et al. Among authors: leung akl. FEBS J. 2022 Dec;289(23):7399-7410. doi: 10.1111/febs.16142. Epub 2021 Sep 13. FEBS J. 2022. PMID: 34323016 Free PMC article.

2

Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm.

Leung AK, Vyas S, Rood JE, Bhutkar A, Sharp PA, Chang P. Leung AK, et al. Mol Cell. 2011 May 20;42(4):489-99. doi: 10.1016/j.molcel.2011.04.015. Mol Cell. 2011. PMID: 21596313 Free PMC article.

3

Methods for purification of proteins associated with cellular poly(ADP-ribose) and PARP-specific poly(ADP-ribose).

Rood JE, Leung AK, Chang P. Rood JE, et al. Methods Mol Biol. 2011;780:153-64. doi: 10.1007/978-1-61779-270-0_10. Methods Mol Biol. 2011. PMID: 21870260 Free PMC article.

4

Poly(ADP-ribose) regulates post-transcriptional gene regulation in the cytoplasm.

Leung A, Todorova T, Ando Y, Chang P. Leung A, et al. RNA Biol. 2012 May;9(5):542-8. doi: 10.4161/rna.19899. Epub 2012 May 1. RNA Biol. 2012. PMID: 22531498 Free PMC article.

5

ENPP1 processes protein ADP-ribosylation in vitro.

Palazzo L, Daniels CM, Nettleship JE, Rahman N, McPherson RL, Ong SE, Kato K, Nureki O, Leung AK, Ahel I. Palazzo L, et al. FEBS J. 2016 Sep;283(18):3371-88. doi: 10.1111/febs.13811. Epub 2016 Aug 5. FEBS J. 2016. PMID: 27406238 Free PMC article.

6

ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence.

McPherson RL, Abraham R, Sreekumar E, Ong SE, Cheng SJ, Baxter VK, Kistemaker HA, Filippov DV, Griffin DE, Leung AK. McPherson RL, et al. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1666-1671. doi: 10.1073/pnas.1621485114. Epub 2017 Jan 31. Proc Natl Acad Sci U S A. 2017. PMID: 28143925 Free PMC article.

7

ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication.

Abraham R, Hauer D, McPherson RL, Utt A, Kirby IT, Cohen MS, Merits A, Leung AKL, Griffin DE. Abraham R, et al. Among authors: leung akl. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10457-E10466. doi: 10.1073/pnas.1812130115. Epub 2018 Oct 15. Proc Natl Acad Sci U S A. 2018. PMID: 30322911 Free PMC article.

8

ELTA: Enzymatic Labeling of Terminal ADP-Ribose.

Ando Y, Elkayam E, McPherson RL, Dasovich M, Cheng SJ, Voorneveld J, Filippov DV, Ong SE, Joshua-Tor L, Leung AKL. Ando Y, et al. Among authors: leung akl. Mol Cell. 2019 Feb 21;73(4):845-856.e5. doi: 10.1016/j.molcel.2018.12.022. Epub 2019 Jan 31. Mol Cell. 2019. PMID: 30712989 Free PMC article.

9

High-Throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain.

Dasovich M, Zhuo J, Goodman JA, Thomas A, McPherson RL, Jayabalan AK, Busa VF, Cheng SJ, Murphy BA, Redinger KR, Alhammad YMO, Fehr AR, Tsukamoto T, Slusher BS, Bosch J, Wei H, Leung AKL. Dasovich M, et al. Among authors: leung akl. ACS Chem Biol. 2022 Jan 21;17(1):17-23. doi: 10.1021/acschembio.1c00721. Epub 2021 Dec 14. ACS Chem Biol. 2022. PMID: 34904435

10

Truncated PARP1 mediates ADP-ribosylation of RNA polymerase III for apoptosis.

Chen Q, Ma K, Liu X, Chen SH, Li P, Yu Y, Leung AKL, Yu X. Chen Q, et al. Among authors: leung akl. Cell Discov. 2022 Jan 18;8(1):3. doi: 10.1038/s41421-021-00355-1. Cell Discov. 2022. PMID: 35039483 Free PMC article.

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