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CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis.
di Ronza A, Bajaj L, Sharma J, Sanagasetti D, Lotfi P, Adamski CJ, Collette J, Palmieri M, Amawi A, Popp L, Chang KT, Meschini MC, Leung HE, Segatori L, Simonati A, Sifers RN, Santorelli FM, Sardiello M. di Ronza A, et al. Among authors: leung he. Nat Cell Biol. 2018 Dec;20(12):1370-1377. doi: 10.1038/s41556-018-0228-7. Epub 2018 Nov 5. Nat Cell Biol. 2018. PMID: 30397314 Free PMC article.
Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model.
Bissig-Choisat B, Wang L, Legras X, Saha PK, Chen L, Bell P, Pankowicz FP, Hill MC, Barzi M, Leyton CK, Leung HE, Kruse RL, Himes RW, Goss JA, Wilson JM, Chan L, Lagor WR, Bissig KD. Bissig-Choisat B, et al. Among authors: leung he. Nat Commun. 2015 Jun 17;6:7339. doi: 10.1038/ncomms8339. Nat Commun. 2015. PMID: 26081744 Free PMC article.
Nuclear S-nitrosylation impacts tissue regeneration in zebrafish.
Matrone G, Jung SY, Choi JM, Jain A, Leung HE, Rajapakshe K, Coarfa C, Rodor J, Denvir MA, Baker AH, Cooke JP. Matrone G, et al. Among authors: leung he. Nat Commun. 2021 Nov 1;12(1):6282. doi: 10.1038/s41467-021-26621-0. Nat Commun. 2021. PMID: 34725362 Free PMC article.
Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes.
Baxter PA, Lin Q, Mao H, Kogiso M, Zhao X, Liu Z, Huang Y, Voicu H, Gurusiddappa S, Su JM, Adesina AM, Perlaky L, Dauser RC, Leung HC, Muraszko KM, Heth JA, Fan X, Lau CC, Man TK, Chintagumpala M, Li XN. Baxter PA, et al. Acta Neuropathol Commun. 2014 Dec 20;2:160. doi: 10.1186/s40478-014-0160-4. Acta Neuropathol Commun. 2014. PMID: 25526772 Free PMC article.
14 results