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Edwardsiella tarda - virulence mechanisms of an emerging gastroenteritis pathogen.
Leung KY, Siame BA, Tenkink BJ, Noort RJ, Mok YK. Leung KY, et al. Microbes Infect. 2012 Jan;14(1):26-34. doi: 10.1016/j.micinf.2011.08.005. Epub 2011 Sep 1. Microbes Infect. 2012. PMID: 21924375 Review.
Internalization and cytotoxicity are important virulence mechanisms in Vibrio-fish epithelial cell interactions.
Wang XH, Oon HL, Ho GW, Wong WS, Lim TM, Leung KY. Wang XH, et al. Among authors: leung ky. Microbiology (Reading). 1998 Nov;144 ( Pt 11):2987-3002. doi: 10.1099/00221287-144-11-2987. Microbiology (Reading). 1998. PMID: 9846734
Use of green fluorescent protein (GFP) to study the invasion pathways of Edwardsiella tarda in in vivo and in vitro fish models.
Ling SHM, Wang XH, Xie L, Lim TM, Leung KY. Ling SHM, et al. Among authors: leung ky. Microbiology (Reading). 2000 Jan;146 ( Pt 1):7-19. doi: 10.1099/00221287-146-1-7. Microbiology (Reading). 2000. PMID: 10658647
Edwardsiella tarda mutants defective in siderophore production, motility, serum resistance and catalase activity.
Mathew JA, Tan YP, Srinivasa Rao PS, Lim TM, Leung KY. Mathew JA, et al. Among authors: leung ky. Microbiology (Reading). 2001 Feb;147(Pt 2):449-457. doi: 10.1099/00221287-147-2-449. Microbiology (Reading). 2001. PMID: 11158362
Green fluorescent protein-tagged Edwardsiella tarda reveals portal of entry in fish.
Ling SH, Wang XH, Lim TM, Leung KY. Ling SH, et al. Among authors: leung ky. FEMS Microbiol Lett. 2001 Jan 15;194(2):239-43. doi: 10.1111/j.1574-6968.2001.tb09476.x. FEMS Microbiol Lett. 2001. PMID: 11164315
Opsonized virulent Edwardsiella tarda strains are able to adhere to and survive and replicate within fish phagocytes but fail to stimulate reactive oxygen intermediates.
Srinivasa Rao PS, Lim TM, Leung KY. Srinivasa Rao PS, et al. Among authors: leung ky. Infect Immun. 2001 Sep;69(9):5689-97. doi: 10.1128/iai.69.9.5689-5697.2001. Infect Immun. 2001. PMID: 11500445 Free PMC article.
Comparative proteomic analysis of extracellular proteins of Edwardsiella tarda.
Tan YP, Lin Q, Wang XH, Joshi S, Hew CL, Leung KY. Tan YP, et al. Among authors: leung ky. Infect Immun. 2002 Nov;70(11):6475-80. doi: 10.1128/iai.70.11.6475-6480.2002. Infect Immun. 2002. PMID: 12379732 Free PMC article.
Functional genomics approach to the identification of virulence genes involved in Edwardsiella tarda pathogenesis.
Srinivasa Rao PS, Lim TM, Leung KY. Srinivasa Rao PS, et al. Among authors: leung ky. Infect Immun. 2003 Mar;71(3):1343-51. doi: 10.1128/iai.71.3.1343-1351.2003. Infect Immun. 2003. PMID: 12595451 Free PMC article.
A major catalase (KatB) that is required for resistance to H2O2 and phagocyte-mediated killing in Edwardsiella tarda.
Srinivasa Rao PS, Yamada Y, Leung KY. Srinivasa Rao PS, et al. Among authors: leung ky. Microbiology (Reading). 2003 Sep;149(Pt 9):2635-2644. doi: 10.1099/mic.0.26478-0. Microbiology (Reading). 2003. PMID: 12949187
A type III secretion system is required for Aeromonas hydrophila AH-1 pathogenesis.
Yu HB, Rao PS, Lee HC, Vilches S, Merino S, Tomas JM, Leung KY. Yu HB, et al. Among authors: leung ky. Infect Immun. 2004 Mar;72(3):1248-56. doi: 10.1128/iai.72.3.1248-1256.2004. Infect Immun. 2004. PMID: 14977925 Free PMC article.
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