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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.
Porter DL, Levine BL, Kalos M, Bagg A, June CH. Porter DL, et al. Among authors: levine bl. N Engl J Med. 2011 Aug 25;365(8):725-33. doi: 10.1056/NEJMoa1103849. Epub 2011 Aug 10. N Engl J Med. 2011. PMID: 21830940 Free PMC article. Clinical Trial.
Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection.
Levine BL, Bernstein WB, Aronson NE, Schlienger K, Cotte J, Perfetto S, Humphries MJ, Ratto-Kim S, Birx DL, Steffens C, Landay A, Carroll RG, June CH. Levine BL, et al. Nat Med. 2002 Jan;8(1):47-53. doi: 10.1038/nm0102-47. Nat Med. 2002. PMID: 11786906 Clinical Trial.
TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted T cells specific for autologous tumor in late-stage ovarian cancer patients.
Schlienger K, Chu CS, Woo EY, Rivers PM, Toll AJ, Hudson B, Maus MV, Riley JL, Choi Y, Coukos G, Kaiser LR, Rubin SC, Levine BL, Carroll RG, June CH. Schlienger K, et al. Among authors: levine bl. Clin Cancer Res. 2003 Apr;9(4):1517-27. Clin Cancer Res. 2003. PMID: 12684428
Adoptive transfer of costimulated T cells induces lymphocytosis in patients with relapsed/refractory non-Hodgkin lymphoma following CD34+-selected hematopoietic cell transplantation.
Laport GG, Levine BL, Stadtmauer EA, Schuster SJ, Luger SM, Grupp S, Bunin N, Strobl FJ, Cotte J, Zheng Z, Gregson B, Rivers P, Vonderheide RH, Liebowitz DN, Porter DL, June CH. Laport GG, et al. Among authors: levine bl. Blood. 2003 Sep 15;102(6):2004-13. doi: 10.1182/blood-2003-01-0095. Epub 2003 May 22. Blood. 2003. PMID: 12763934 Clinical Trial.
A novel system for simultaneous in vivo tracking and biological assessment of leukemia cells and ex vivo generated leukemia-reactive cytotoxic T cells.
Sauer MG, Ericson ME, Weigel BJ, Herron MJ, Panoskaltsis-Mortari A, Kren BT, Levine BL, Serody JS, June CH, Taylor PA, Blazar BR. Sauer MG, et al. Among authors: levine bl. Cancer Res. 2004 Jun 1;64(11):3914-21. doi: 10.1158/0008-5472.CAN-03-3991. Cancer Res. 2004. PMID: 15173002
A phase 1 trial of donor lymphocyte infusions expanded and activated ex vivo via CD3/CD28 costimulation.
Porter DL, Levine BL, Bunin N, Stadtmauer EA, Luger SM, Goldstein S, Loren A, Phillips J, Nasta S, Perl A, Schuster S, Tsai D, Sohal A, Veloso E, Emerson S, June CH. Porter DL, et al. Among authors: levine bl. Blood. 2006 Feb 15;107(4):1325-31. doi: 10.1182/blood-2005-08-3373. Epub 2005 Nov 3. Blood. 2006. PMID: 16269610 Clinical Trial.
Gene transfer in humans using a conditionally replicating lentiviral vector.
Levine BL, Humeau LM, Boyer J, MacGregor RR, Rebello T, Lu X, Binder GK, Slepushkin V, Lemiale F, Mascola JR, Bushman FD, Dropulic B, June CH. Levine BL, et al. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17372-7. doi: 10.1073/pnas.0608138103. Epub 2006 Nov 7. Proc Natl Acad Sci U S A. 2006. PMID: 17090675 Free PMC article.
CD28 costimulation is essential for human T regulatory expansion and function.
Golovina TN, Mikheeva T, Suhoski MM, Aqui NA, Tai VC, Shan X, Liu R, Balcarcel RR, Fisher N, Levine BL, Carroll RG, Warner N, Blazar BR, June CH, Riley JL. Golovina TN, et al. Among authors: levine bl. J Immunol. 2008 Aug 15;181(4):2855-68. doi: 10.4049/jimmunol.181.4.2855. J Immunol. 2008. PMID: 18684977 Free PMC article.
Adoptive immunotherapy: good habits instilled at youth have long-term benefits.
Paulos CM, Suhoski MM, Plesa G, Jiang T, Basu S, Golovina TN, Jiang S, Aqui NA, Powell DJ Jr, Levine BL, Carroll RG, Riley JL, June CH. Paulos CM, et al. Among authors: levine bl. Immunol Res. 2008;42(1-3):182-96. doi: 10.1007/s12026-008-8070-9. Immunol Res. 2008. PMID: 18949448 Free PMC article. Review.
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