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713 results
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Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders.
Levine RL, Pardanani A, Tefferi A, Gilliland DG. Levine RL, et al. Nat Rev Cancer. 2007 Sep;7(9):673-83. doi: 10.1038/nrc2210. Nat Rev Cancer. 2007. PMID: 17721432 Review.
Genetics of myeloid malignancies: pathogenetic and clinical implications.
Fröhling S, Scholl C, Gilliland DG, Levine RL. Fröhling S, et al. Among authors: levine rl. J Clin Oncol. 2005 Sep 10;23(26):6285-95. doi: 10.1200/JCO.2005.05.010. J Clin Oncol. 2005. PMID: 16155011 Review.
Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation.
Lu X, Levine R, Tong W, Wernig G, Pikman Y, Zarnegar S, Gilliland DG, Lodish H. Lu X, et al. Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):18962-7. doi: 10.1073/pnas.0509714102. Epub 2005 Dec 19. Proc Natl Acad Sci U S A. 2005. PMID: 16365288 Free PMC article.
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.
Pikman Y, Lee BH, Mercher T, McDowell E, Ebert BL, Gozo M, Cuker A, Wernig G, Moore S, Galinsky I, DeAngelo DJ, Clark JJ, Lee SJ, Golub TR, Wadleigh M, Gilliland DG, Levine RL. Pikman Y, et al. Among authors: levine rl. PLoS Med. 2006 Jul;3(7):e270. doi: 10.1371/journal.pmed.0030270. PLoS Med. 2006. PMID: 16834459 Free PMC article.
SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
Duan Z, Bradner JE, Greenberg E, Levine R, Foster R, Mahoney J, Seiden MV. Duan Z, et al. Clin Cancer Res. 2006 Nov 15;12(22):6844-52. doi: 10.1158/1078-0432.CCR-06-1330. Clin Cancer Res. 2006. PMID: 17121906
Role of JAK-STAT signaling in the pathogenesis of myeloproliferative disorders.
Levine RL, Wernig G. Levine RL, et al. Hematology Am Soc Hematol Educ Program. 2006:233-9, 510. doi: 10.1182/asheducation-2006.1.233. Hematology Am Soc Hematol Educ Program. 2006. PMID: 17124066 Review.
JAK-2 mutations and their relevance to myeloproliferative disease.
Levine RL, Gilliland DG. Levine RL, et al. Curr Opin Hematol. 2007 Jan;14(1):43-7. doi: 10.1097/00062752-200701000-00009. Curr Opin Hematol. 2007. PMID: 17133099 Review.
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.
Lee JC, Vivanco I, Beroukhim R, Huang JH, Feng WL, DeBiasi RM, Yoshimoto K, King JC, Nghiemphu P, Yuza Y, Xu Q, Greulich H, Thomas RK, Paez JG, Peck TC, Linhart DJ, Glatt KA, Getz G, Onofrio R, Ziaugra L, Levine RL, Gabriel S, Kawaguchi T, O'Neill K, Khan H, Liau LM, Nelson SF, Rao PN, Mischel P, Pieper RO, Cloughesy T, Leahy DJ, Sellers WR, Sawyers CL, Meyerson M, Mellinghoff IK. Lee JC, et al. Among authors: levine rl. PLoS Med. 2006 Dec;3(12):e485. doi: 10.1371/journal.pmed.0030485. PLoS Med. 2006. PMID: 17177598 Free PMC article.
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis.
Scott LM, Tong W, Levine RL, Scott MA, Beer PA, Stratton MR, Futreal PA, Erber WN, McMullin MF, Harrison CN, Warren AJ, Gilliland DG, Lodish HF, Green AR. Scott LM, et al. Among authors: levine rl. N Engl J Med. 2007 Feb 1;356(5):459-68. doi: 10.1056/NEJMoa065202. N Engl J Med. 2007. PMID: 17267906 Free PMC article.
FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia.
Lee BH, Tothova Z, Levine RL, Anderson K, Buza-Vidas N, Cullen DE, McDowell EP, Adelsperger J, Fröhling S, Huntly BJ, Beran M, Jacobsen SE, Gilliland DG. Lee BH, et al. Among authors: levine rl. Cancer Cell. 2007 Oct;12(4):367-80. doi: 10.1016/j.ccr.2007.08.031. Cancer Cell. 2007. PMID: 17936561 Free PMC article.
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