Levitzki A - Search Results

1

Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins.

Párrizas M, Gazit A, Levitzki A, Wertheimer E, LeRoith D. Párrizas M, et al. Among authors: levitzki a. Endocrinology. 1997 Apr;138(4):1427-33. doi: 10.1210/endo.138.4.5092. Endocrinology. 1997. PMID: 9075698

2

Development of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics.

Blum G, Gazit A, Levitzki A. Blum G, et al. Among authors: levitzki a. J Biol Chem. 2003 Oct 17;278(42):40442-54. doi: 10.1074/jbc.M305490200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12869569 Free article.

AG 538 is a substrate-competitive inhibitor of the IGF-1 receptor (IGF-1R), with an IC50 = 61 nM in a cell-free kinase assay (Blum, G., Gazit, A., and Levitzki, A. (2000) Biochemistry 39, 15705-15712). ...These AG 538 bioisosteres possess simila …

AG 538 is a substrate-competitive inhibitor of the IGF-1 receptor (IGF-1R), with an IC50 = 61 nM in a cell-free kinase assay ( …

3

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors.

Gazit A, Yaish P, Gilon C, Levitzki A. Gazit A, et al. Among authors: levitzki a. J Med Chem. 1989 Oct;32(10):2344-52. doi: 10.1021/jm00130a020. J Med Chem. 1989. PMID: 2552117

4

Tyrphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation.

Lyall RM, Zilberstein A, Gazit A, Gilon C, Levitzki A, Schlessinger J. Lyall RM, et al. Among authors: levitzki a. J Biol Chem. 1989 Aug 25;264(24):14503-9. J Biol Chem. 1989. PMID: 2788167 Free article.

5

Effects of tyrphostins, protein kinase inhibitors, on human immunodeficiency virus type 1 integrase.

Mazumder A, Gazit A, Levitzki A, Nicklaus M, Yung J, Kohlhagen G, Pommier Y. Mazumder A, et al. Among authors: levitzki a. Biochemistry. 1995 Nov 21;34(46):15111-22. doi: 10.1021/bi00046a018. Biochemistry. 1995. PMID: 7578125

6

Tyrosine kinase inhibition: an approach to drug development.

Levitzki A, Gazit A. Levitzki A, et al. Science. 1995 Mar 24;267(5205):1782-8. doi: 10.1126/science.7892601. Science. 1995. PMID: 7892601 Review.

7

Tyrphostin induced growth inhibition: correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia.

Kaur G, Gazit A, Levitzki A, Stowe E, Cooney DA, Sausville EA. Kaur G, et al. Among authors: levitzki a. Anticancer Drugs. 1994 Apr;5(2):213-22. Anticancer Drugs. 1994. PMID: 8049505

8

Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins.

Osherov N, Gazit A, Gilon C, Levitzki A. Osherov N, et al. Among authors: levitzki a. J Biol Chem. 1993 May 25;268(15):11134-42. J Biol Chem. 1993. PMID: 8098709 Free article.

9

Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program.

Posner I, Engel M, Gazit A, Levitzki A. Posner I, et al. Among authors: levitzki a. Mol Pharmacol. 1994 Apr;45(4):673-83. Mol Pharmacol. 1994. PMID: 8183246

10

Tyrphostins. 5. Potent inhibitors of platelet-derived growth factor receptor tyrosine kinase: structure-activity relationships in quinoxalines, quinolines, and indole tyrphostins.

Gazit A, App H, McMahon G, Chen J, Levitzki A, Bohmer FD. Gazit A, et al. Among authors: levitzki a. J Med Chem. 1996 May 24;39(11):2170-7. doi: 10.1021/jm950727b. J Med Chem. 1996. PMID: 8667360

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

341 results

Search Page