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Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety.
Scholz O, Huß E, Otter S, Herebian D, Hamacher A, Levy LM, Hristeva S, Sanz M, Ajani H, Puentes AR, Hoffmann T, Hogeback J, Unger A, Terheyden S, Reina do Fundo M, Dewidar B, Roden M, Lammert E. Scholz O, et al. Among authors: levy lm. Mol Metab. 2023 Sep;75:101775. doi: 10.1016/j.molmet.2023.101775. Epub 2023 Jul 12. Mol Metab. 2023. PMID: 37451343 Free PMC article.
Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Quambusch L, Depta L, Landel I, Lubeck M, Kirschner T, Nabert J, Uhlenbrock N, Weisner J, Kostka M, Levy LM, Schultz-Fademrecht C, Glanemann F, Althoff K, Müller MP, Siveke JT, Rauh D. Quambusch L, et al. Among authors: levy lm. Nat Commun. 2021 Sep 6;12(1):5297. doi: 10.1038/s41467-021-25512-8. Nat Commun. 2021. PMID: 34489430 Free PMC article.
An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-κB-Utilizing a Reversible Covalent Tethering Approach.
Wolter M, Valenti D, Cossar PJ, Hristeva S, Levy LM, Genski T, Hoffmann T, Brunsveld L, Tzalis D, Ottmann C. Wolter M, et al. Among authors: levy lm. J Med Chem. 2021 Jun 24;64(12):8423-8436. doi: 10.1021/acs.jmedchem.1c00401. Epub 2021 Jun 2. J Med Chem. 2021. PMID: 34076416 Free PMC article.
Set-up and screening of a fragment library targeting the 14-3-3 protein interface.
Valenti D, Neves JF, Cantrelle FX, Hristeva S, Lentini Santo D, Obšil T, Hanoulle X, Levy LM, Tzalis D, Landrieu I, Ottmann C. Valenti D, et al. Among authors: levy lm. Medchemcomm. 2019 Jul 22;10(10):1796-1802. doi: 10.1039/c9md00215d. eCollection 2019 Oct 1. Medchemcomm. 2019. PMID: 31814953 Free PMC article.
Genetics of amyotrophic lateral sclerosis.
Gorodenker J, Levy LM. Gorodenker J, et al. Among authors: levy lm. AJNR Am J Neuroradiol. 2014 Dec;35(12):2254-6. doi: 10.3174/ajnr.A3831. Epub 2014 Jan 23. AJNR Am J Neuroradiol. 2014. PMID: 24457822 Free PMC article. No abstract available.
145 results