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Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.
Lohman DC, Forouhar F, Beebe ET, Stefely MS, Minogue CE, Ulbrich A, Stefely JA, Sukumar S, Luna-Sánchez M, Jochem A, Lew S, Seetharaman J, Xiao R, Wang H, Westphall MS, Wrobel RL, Everett JK, Mitchell JC, López LC, Coon JJ, Tong L, Pagliarini DJ. Lohman DC, et al. Among authors: lew s. Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):E4697-705. doi: 10.1073/pnas.1413128111. Epub 2014 Oct 22. Proc Natl Acad Sci U S A. 2014. PMID: 25339443 Free PMC article.
Structures of bacterial biosynthetic arginine decarboxylases.
Forouhar F, Lew S, Seetharaman J, Xiao R, Acton TB, Montelione GT, Tong L. Forouhar F, et al. Among authors: lew s. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 1;66(Pt 12):1562-6. doi: 10.1107/S1744309110040649. Epub 2010 Nov 16. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 21139196 Free PMC article.
Structure of a specialized acyl carrier protein essential for lipid A biosynthesis with very long-chain fatty acids in open and closed conformations.
Ramelot TA, Rossi P, Forouhar F, Lee HW, Yang Y, Ni S, Unser S, Lew S, Seetharaman J, Xiao R, Acton TB, Everett JK, Prestegard JH, Hunt JF, Montelione GT, Kennedy MA. Ramelot TA, et al. Among authors: lew s. Biochemistry. 2012 Sep 18;51(37):7239-49. doi: 10.1021/bi300546b. Epub 2012 Sep 7. Biochemistry. 2012. PMID: 22876860 Free PMC article.
Solution NMR and X-ray crystal structures of Pseudomonas syringae Pspto_3016 from protein domain family PF04237 (DUF419) adopt a "double wing" DNA binding motif.
Feldmann EA, Seetharaman J, Ramelot TA, Lew S, Zhao L, Hamilton K, Ciccosanti C, Xiao R, Acton TB, Everett JK, Tong L, Montelione GT, Kennedy MA. Feldmann EA, et al. Among authors: lew s. J Struct Funct Genomics. 2012 Sep;13(3):155-62. doi: 10.1007/s10969-012-9140-8. Epub 2012 Aug 3. J Struct Funct Genomics. 2012. PMID: 22865330 Free PMC article.
Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations.
Froese DS, Forouhar F, Tran TH, Vollmar M, Kim YS, Lew S, Neely H, Seetharaman J, Shen Y, Xiao R, Acton TB, Everett JK, Cannone G, Puranik S, Savitsky P, Krojer T, Pilka ES, Kiyani W, Lee WH, Marsden BD, von Delft F, Allerston CK, Spagnolo L, Gileadi O, Montelione GT, Oppermann U, Yue WW, Tong L. Froese DS, et al. Among authors: lew s. Structure. 2013 Jul 2;21(7):1182-92. doi: 10.1016/j.str.2013.05.001. Epub 2013 Jun 20. Structure. 2013. PMID: 23791943 Free PMC article.
Structural and biochemical characterization of the bilin lyase CpcS from Thermosynechococcus elongatus.
Kronfel CM, Kuzin AP, Forouhar F, Biswas A, Su M, Lew S, Seetharaman J, Xiao R, Everett JK, Ma LC, Acton TB, Montelione GT, Hunt JF, Paul CE, Dragomani TM, Boutaghou MN, Cole RB, Riml C, Alvey RM, Bryant DA, Schluchter WM. Kronfel CM, et al. Among authors: lew s. Biochemistry. 2013 Dec 3;52(48):8663-76. doi: 10.1021/bi401192z. Epub 2013 Nov 19. Biochemistry. 2013. PMID: 24215428 Free PMC article.
Design of activated serine-containing catalytic triads with atomic-level accuracy.
Rajagopalan S, Wang C, Yu K, Kuzin AP, Richter F, Lew S, Miklos AE, Matthews ML, Seetharaman J, Su M, Hunt JF, Cravatt BF, Baker D. Rajagopalan S, et al. Among authors: lew s. Nat Chem Biol. 2014 May;10(5):386-91. doi: 10.1038/nchembio.1498. Epub 2014 Apr 6. Nat Chem Biol. 2014. PMID: 24705591 Free PMC article.
396 results