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Synthesis and adrenoreceptor blocking action of aziridinium ions derived from phenoxybenzamine and dibenamine.
Henkel JG, Portoghese PS, Miller JW, Lewis P. Henkel JG, et al. Among authors: lewis p. J Med Chem. 1976 Jan;19(1):6-10. doi: 10.1021/jm00223a002. J Med Chem. 1976. PMID: 1536
Discovery of (+)-N-(3-aminopropyl)-N-[1-(5-benzyl-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl)-2-methylpropyl]-4-methylbenzamide (AZD4877), a kinesin spindle protein inhibitor and potential anticancer agent.
Theoclitou ME, Aquila B, Block MH, Brassil PJ, Castriotta L, Code E, Collins MP, Davies AM, Deegan T, Ezhuthachan J, Filla S, Freed E, Hu H, Huszar D, Jayaraman M, Lawson D, Lewis PM, Nadella MV, Oza V, Padmanilayam M, Pontz T, Ronco L, Russell D, Whitston D, Zheng X. Theoclitou ME, et al. Among authors: lewis pm. J Med Chem. 2011 Oct 13;54(19):6734-50. doi: 10.1021/jm200629m. Epub 2011 Sep 7. J Med Chem. 2011. PMID: 21899292
Identification and Optimization of Benzimidazole Sulfonamides as Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists with in Vivo Activity.
Hennessy EJ, Oza V, Adam A, Byth K, Castriotta L, Grewal G, Hamilton GA, Kamhi VM, Lewis P, Li D, Lyne P, Ă–ster L, Rooney MT, Saeh JC, Sha L, Su Q, Wen S, Xue Y, Yang B. Hennessy EJ, et al. Among authors: lewis p. J Med Chem. 2015 Sep 10;58(17):7057-75. doi: 10.1021/acs.jmedchem.5b01078. Epub 2015 Aug 26. J Med Chem. 2015. PMID: 26291341
Inflated Density Ratio and Its Variation and Generalization for Computing Marginal Likelihoods.
Wang YB, Chen MH, Shi W, Lewis P, Kuo L. Wang YB, et al. Among authors: lewis p. J Korean Stat Soc. 2020 Mar;49(1):244-263. doi: 10.1007/s42952-019-00013-z. Epub 2020 Jan 1. J Korean Stat Soc. 2020. PMID: 33071541
AI-RADS: An Artificial Intelligence Curriculum for Residents.
Lindqwister AL, Hassanpour S, Lewis PJ, Sin JM. Lindqwister AL, et al. Among authors: lewis pj. Acad Radiol. 2020 Oct 15:S1076-6332(20)30556-0. doi: 10.1016/j.acra.2020.09.017. Online ahead of print. Acad Radiol. 2020. PMID: 33071185 Free PMC article.
Reply to: "Light and Shade in Patrick Lewis et al's Paper on the First Photographs of Parkinson's Disease".
Lewis PA, Plun-Favreau H, Rowley M, Spillane J. Lewis PA, et al. Mov Disord. 2020 Oct;35(10):1882. doi: 10.1002/mds.28237. Mov Disord. 2020. PMID: 33068469 No abstract available.
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.
Jain SU, Khazaei S, Marchione DM, Lundgren SM, Wang X, Weinberg DN, Deshmukh S, Juretic N, Lu C, Allis CD, Garcia BA, Jabado N, Lewis PW. Jain SU, et al. Among authors: lewis pw. Proc Natl Acad Sci U S A. 2020 Oct 16:202006076. doi: 10.1073/pnas.2006076117. Online ahead of print. Proc Natl Acad Sci U S A. 2020. PMID: 33067396
H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2.
Jain SU, Rashoff AQ, Krabbenhoft SD, Hoelper D, Do TJ, Gibson TJ, Lundgren SM, Bondra ER, Deshmukh S, Harutyunyan AS, Juretic N, Jabado N, Harrison MM, Lewis PW. Jain SU, et al. Among authors: lewis pw. Mol Cell. 2020 Oct 7:S1097-2765(20)30680-8. doi: 10.1016/j.molcel.2020.09.028. Online ahead of print. Mol Cell. 2020. PMID: 33049227
Establishment of long-term ostracod epidermal culture.
Morgan SR, Paletto L, Rumney B, Malik FT, White N, Lewis PN, Parker AR, Holden S, Meek KM, Albon J. Morgan SR, et al. Among authors: lewis pn. In Vitro Cell Dev Biol Anim. 2020 Oct 9. doi: 10.1007/s11626-020-00508-8. Online ahead of print. In Vitro Cell Dev Biol Anim. 2020. PMID: 33034828
AZD4320, a dual inhibitor of Bcl-2 and Bcl-xL, induces tumor regression in hematological cancer models without dose-limiting thrombocytopenia.
Balachander SB, Criscione SW, Byth KF, Cidado J, Adam A, MacIntyre T, Wen S, Lawson D, Burke K, Lubinski TJ, Tyner JW, Kurtz SE, McWeeney SK, Varnes J, Diebold RB, Gero TW, Ioannidis S, Hennessy EJ, McCoull W, Saeh JC, Lewis P, Tabatabai A, Tavana O, Su N, Schuller A, Garnett MJ, Jaaks P, Coker EA, Gregory GP, Newbold A, Johnstone RW, Gangl E, Wild M, Zinda M, Secrist JP, Davies BR, Fawell SE, Gibbons FD. Balachander SB, et al. Among authors: lewis p. Clin Cancer Res. 2020 Sep 28:clincanres.0863.2020. doi: 10.1158/1078-0432.CCR-20-0863. Online ahead of print. Clin Cancer Res. 2020. PMID: 32988967
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