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226 results
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Clinical drug development: an analysis of phase II trials, 1970-1985.
Marsoni S, Hoth D, Simon R, Leyland-Jones B, De Rosa M, Wittes RE. Marsoni S, et al. Cancer Treat Rep. 1987 Jan;71(1):71-80. Cancer Treat Rep. 1987. PMID: 3791270
Phase I study of elliptinium (2-N-methyl-9-hydroxyellipticinium).
Einzig AI, Gralla RJ, Leyland-Jones BR, Kelsen DP, Cibas I, Lewis E, Greenberg E. Einzig AI, et al. Cancer Invest. 1985;3(3):235-41. doi: 10.3109/07357908509039784. Cancer Invest. 1985. PMID: 4005651
Phase I clinical trial and pharmacokinetics of 4'-carboxyphthalato(1,2-diaminocyclohexane)platinum(II).
Kelsen DP, Scher H, Alcock N, Leyland-Jones B, Donner A, Williams L, Greene G, Burchenal JH, Tan C, Philips FS, Young CW. Kelsen DP, et al. Cancer Res. 1982 Nov;42(11):4831-5. Cancer Res. 1982. PMID: 7127319
Phase I and clinical pharmacology studies of intravenous and oral administration of 4-demethoxydaunorubicin in patients with advanced cancer.
Berman E, Wittes RE, Leyland-Jones B, Casper ES, Gralla RJ, Howard J, Williams L, Baratz R, Young CW. Berman E, et al. Cancer Res. 1983 Dec;43(12 Pt 1):6096-101. Cancer Res. 1983. PMID: 6580068
2'-Deoxycoformycin (pentostatin) for lymphoid malignancies. Rational development of an active new drug.
O'Dwyer PJ, Wagner B, Leyland-Jones B, Wittes RE, Cheson BD, Hoth DF. O'Dwyer PJ, et al. Ann Intern Med. 1988 May;108(5):733-43. doi: 10.7326/0003-4819-108-5-733. Ann Intern Med. 1988. PMID: 3282467 Review.
Phase I and II clinical and pharmacological study of 4-demethoxydaunorubicin (idarubicin) in adult patients with acute leukemia.
Daghestani AN, Arlin ZA, Leyland-Jones B, Gee TS, Kempin SJ, Mertelsmann R, Budman D, Schulman P, Baratz R, Williams L, et al. Daghestani AN, et al. Cancer Res. 1985 Mar;45(3):1408-12. Cancer Res. 1985. PMID: 3855696
4-Ipomeanol: a novel investigational new drug for lung cancer.
Christian MC, Wittes RE, Leyland-Jones B, McLemore TL, Smith AC, Grieshaber CK, Chabner BA, Boyd MR. Christian MC, et al. J Natl Cancer Inst. 1989 Aug 2;81(15):1133-43. doi: 10.1093/jnci/81.15.1133. J Natl Cancer Inst. 1989. PMID: 2664191 Review.
Overview of current status and future direction of clinical trials with 5-fluorouracil in combination with folinic acid.
Grem JL, Hoth DF, Hamilton JM, King SA, Leyland-Jones B. Grem JL, et al. Cancer Treat Rep. 1987 Dec;71(12):1249-64. Cancer Treat Rep. 1987. PMID: 3319136 Review. No abstract available.
Gallium nitrate: the second metal with clinical activity.
Foster BJ, Clagett-Carr K, Hoth D, Leyland-Jones B. Foster BJ, et al. Cancer Treat Rep. 1986 Nov;70(11):1311-9. Cancer Treat Rep. 1986. PMID: 3533251 Review.
The application of a two-stage design for clinical trials in patients with recurrent head and neck cancer.
Eisenberger MA, Ellenberg S, Leyland-Jones B, Friedman M. Eisenberger MA, et al. Med Pediatr Oncol. 1988;16(3):162-8. doi: 10.1002/mpo.2950160303. Med Pediatr Oncol. 1988. PMID: 3288853 Review.
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