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Sleep Disturbances in Chronic Pain: Neurobiology, Assessment, and Treatment in Physical Therapist Practice.
Nijs J, Mairesse O, Neu D, Leysen L, Danneels L, Cagnie B, Meeus M, Moens M, Ickmans K, Goubert D. Nijs J, et al. Among authors: Leysen L. Phys Ther. 2018 May 1;98(5):325-335. doi: 10.1093/ptj/pzy020. Phys Ther. 2018. PMID: 29425327 Review.
This review article applies the current understanding of insomnia to clinical practice, including assessment and conservative treatment of insomnia in people with chronic pain. Cognitive-behavioral therapy for insomnia can be efficacious for improvements in sleep initiatio …
This review article applies the current understanding of insomnia to clinical practice, including assessment and conservative treatment of i …
Treatment of central sensitization in patients with chronic pain: time for change?
Nijs J, Leysen L, Vanlauwe J, Logghe T, Ickmans K, Polli A, Malfliet A, Coppieters I, Huysmans E. Nijs J, et al. Among authors: Leysen L. Expert Opin Pharmacother. 2019 Nov;20(16):1961-1970. doi: 10.1080/14656566.2019.1647166. Epub 2019 Jul 29. Expert Opin Pharmacother. 2019. PMID: 31355689 Review.
Introduction: Given our improved understanding of the role of central sensitization (CS) in many patients with chronic pain, it seems rational to account for CS during treatment. Areas covered: First, the treatment rationale based on the complex mechanisms underlying CS in …
Introduction: Given our improved understanding of the role of central sensitization (CS) in many patients with chronic pain, it seems …
Chronic Pain in Breast Cancer Survivors: Nociceptive, Neuropathic, or Central Sensitization Pain?
Leysen L, Adriaenssens N, Nijs J, Pas R, Bilterys T, Vermeir S, Lahousse A, Beckwée D. Leysen L, et al. Pain Pract. 2019 Feb;19(2):183-195. doi: 10.1111/papr.12732. Epub 2018 Nov 15. Pain Pract. 2019. PMID: 30269431 Clinical Trial.
INTRODUCTION: The differentiation between acute and chronic pain can be insufficient for appropriate pain management. The aim of this study was to evaluate the prevalence of the predominant pain type (nociceptive, neuropathic, or central sensitization [CS] …
INTRODUCTION: The differentiation between acute and chronic pain can be insufficient for appropriate pain management. The aim …
Risk factors of pain in breast cancer survivors: a systematic review and meta-analysis.
Leysen L, Beckwée D, Nijs J, Pas R, Bilterys T, Vermeir S, Adriaenssens N. Leysen L, et al. Support Care Cancer. 2017 Dec;25(12):3607-3643. doi: 10.1007/s00520-017-3824-3. Epub 2017 Aug 10. Support Care Cancer. 2017. PMID: 28799015 Review.
Consequently, sequelae, such as pain, are becoming more important. PURPOSE: The purpose of this study was to identify risk factors for the development of pain in breast cancer survivors. ...Lack of uniformity across the studies in defining pain, follow-up, me …
Consequently, sequelae, such as pain, are becoming more important. PURPOSE: The purpose of this study was to identify risk factors fo …
Pain following cancer treatment: Guidelines for the clinical classification of predominant neuropathic, nociceptive and central sensitization pain.
Nijs J, Leysen L, Adriaenssens N, Aguilar Ferrándiz ME, Devoogdt N, Tassenoy A, Ickmans K, Goubert D, van Wilgen CP, Wijma AJ, Kuppens K, Hoelen W, Hoelen A, Moloney N, Meeus M. Nijs J, et al. Among authors: Leysen L. Acta Oncol. 2016 Jun;55(6):659-63. doi: 10.3109/0284186X.2016.1167958. Epub 2016 May 4. Acta Oncol. 2016. PMID: 27142228
RESULTS: The classification of pain following cancer treatment entails two steps: (1) examining the presence of neuropathic pain; and (2) using an algorithm for differentiating predominant nociceptive and central sensitization pain. Step 1 builds on the estab …
RESULTS: The classification of pain following cancer treatment entails two steps: (1) examining the presence of neuropathic pain
Modern pain neuroscience in clinical practice: applied to post-cancer, paediatric and sports-related pain.
Malfliet A, Leysen L, Pas R, Kuppens K, Nijs J, Van Wilgen P, Huysmans E, Goudman L, Ickmans K. Malfliet A, et al. Among authors: Leysen L. Braz J Phys Ther. 2017 Jul-Aug;21(4):225-232. doi: 10.1016/j.bjpt.2017.05.009. Epub 2017 May 19. Braz J Phys Ther. 2017. PMID: 28579013 Free PMC article. Review.
In the last decade, evidence regarding chronic pain has developed exponentially. Numerous studies show that many chronic pain populations show specific neuroplastic changes in the peripheral and central nervous system. ...Therefore, this masterclass article aims at …
In the last decade, evidence regarding chronic pain has developed exponentially. Numerous studies show that many chronic pain
Endogenous pain modulation in children with functional abdominal pain disorders.
Pas R, Rheel E, Van Oosterwijck S, Leysen L, Van De Vijver E, Nijs J, Ickmans K, Meeus M. Pas R, et al. Among authors: Leysen L. Pain. 2019 Aug;160(8):1883-1890. doi: 10.1097/j.pain.0000000000001566. Pain. 2019. PMID: 31335656
Conditioned pain modulation was recorded as an increase in the PPT at the trapezius test site in response to experimental conditioning pain imposed by the cold pressor task (12 ± 1°C). ...Parent-proxy and/or self-reported questionnaires were used to assess child's …
Conditioned pain modulation was recorded as an increase in the PPT at the trapezius test site in response to experimental conditionin …
Explaining pain following cancer: a practical guide for clinicians.
Nijs J, Wijma AJ, Leysen L, Pas R, Willaert W, Hoelen W, Ickmans K, Wilgen CPV. Nijs J, et al. Among authors: Leysen L. Braz J Phys Ther. 2019 Sep-Oct;23(5):367-377. doi: 10.1016/j.bjpt.2018.12.003. Epub 2018 Dec 21. Braz J Phys Ther. 2019. PMID: 30606621 Free PMC article. Review.
Therapists require an in-depth understanding of pain mechanisms, the skills to explain to their patients various pain mechanisms, specific communication skills (e.g. ...Its application is backed-up by mounting evidence supporting the effectiveness of PNE in non-canc …
Therapists require an in-depth understanding of pain mechanisms, the skills to explain to their patients various pain mechanis …
Prevalence and risk factors of sleep disturbances in breast cancersurvivors: systematic review and meta-analyses.
Leysen L, Lahousse A, Nijs J, Adriaenssens N, Mairesse O, Ivakhnov S, Bilterys T, Van Looveren E, Pas R, Beckwée D. Leysen L, et al. Support Care Cancer. 2019 Dec;27(12):4401-4433. doi: 10.1007/s00520-019-04936-5. Epub 2019 Jul 25. Support Care Cancer. 2019. PMID: 31346744
It has been demonstrated that untreated insomnia in BCS negatively impacts mood, physical symptoms, pain sensitivity, fatigue, and quality of life. ...Pain, depressive symptoms, hot flashes, fatigue, non-Caucasian race, and menopausal status were significantly assoc …
It has been demonstrated that untreated insomnia in BCS negatively impacts mood, physical symptoms, pain sensitivity, fatigue, and qu …
Development and feasibility testing of a Pain Neuroscience Education program for children with chronic pain: treatment protocol.
Pas R, Meeus M, Malfliet A, Baert I, Oosterwijck SV, Leysen L, Nijs J, Ickmans K. Pas R, et al. Among authors: Leysen L. Braz J Phys Ther. 2018 May-Jun;22(3):248-253. doi: 10.1016/j.bjpt.2018.02.004. Epub 2018 Mar 4. Braz J Phys Ther. 2018. PMID: 29550259 Free PMC article.
BACKGROUND: Current treatment for adults with chronic pain often includes Pain Neuroscience Education (PNE) to make people understand the nature underlying their pain and thus provides a clear rational for a biopsychosocial approach. ...OBJECTIVES: The aim of …
BACKGROUND: Current treatment for adults with chronic pain often includes Pain Neuroscience Education (PNE) to make people und …
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