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Pain Neuroscience Education for Children with Functional Abdominal Pain Disorders: A Randomized Comparative Pilot Study.
Pas R, Rheel E, Van Oosterwijck S, Foubert A, De Pauw R, Leysen L, Roete A, Nijs J, Meeus M, Ickmans K. Pas R, et al. Among authors: Leysen L. J Clin Med. 2020 Jun 9;9(6):E1797. doi: 10.3390/jcm9061797. J Clin Med. 2020. PMID: 32526929 Free article.
This article explores the effectiveness of a newly developed Pain Neuroscience Education program for children (PNE4Kids) with functional abdominal pain disorder (FAPD). ...Parental pain catastrophizing, the child's functional disability (parental-proxy), p
This article explores the effectiveness of a newly developed Pain Neuroscience Education program for children (PNE4Kids) with functio …
Behavioral Graded Activity+ (BGA+) for Osteoarthritis: A Paradigm Shift from Disease-Based Treatment to Personalized Activity Self-Management.
Nijs J, Ickmans K, Beckwée D, Leysen L. Nijs J, et al. Among authors: Leysen L. J Clin Med. 2020 Jun 9;9(6):E1793. doi: 10.3390/jcm9061793. J Clin Med. 2020. PMID: 32526889 Free article.
To account for the implementation barriers of BGA, we propose adding pain neuroscience education to BGA (referred to as BGA(+)). Rather than focusing on the biomedical (and biomechanical) disease characteristics of OA, pain neuroscience education implies teaching pe …
To account for the implementation barriers of BGA, we propose adding pain neuroscience education to BGA (referred to as BGA(+)). Rath …
Treatment of central sensitization in patients with chronic pain: time for change?
Nijs J, Leysen L, Vanlauwe J, Logghe T, Ickmans K, Polli A, Malfliet A, Coppieters I, Huysmans E. Nijs J, et al. Among authors: Leysen L. Expert Opin Pharmacother. 2019 Nov;20(16):1961-1970. doi: 10.1080/14656566.2019.1647166. Epub 2019 Jul 29. Expert Opin Pharmacother. 2019. PMID: 31355689 Review.
Introduction: Given our improved understanding of the role of central sensitization (CS) in many patients with chronic pain, it seems rational to account for CS during treatment. Areas covered: First, the treatment rationale based on the complex mechanisms underlying CS in …
Introduction: Given our improved understanding of the role of central sensitization (CS) in many patients with chronic pain, it seems …
Prevalence and risk factors of sleep disturbances in breast cancersurvivors: systematic review and meta-analyses.
Leysen L, Lahousse A, Nijs J, Adriaenssens N, Mairesse O, Ivakhnov S, Bilterys T, Van Looveren E, Pas R, Beckwée D. Leysen L, et al. Support Care Cancer. 2019 Dec;27(12):4401-4433. doi: 10.1007/s00520-019-04936-5. Epub 2019 Jul 25. Support Care Cancer. 2019. PMID: 31346744
It has been demonstrated that untreated insomnia in BCS negatively impacts mood, physical symptoms, pain sensitivity, fatigue, and quality of life. ...Pain, depressive symptoms, hot flashes, fatigue, non-Caucasian race, and menopausal status were significantly assoc …
It has been demonstrated that untreated insomnia in BCS negatively impacts mood, physical symptoms, pain sensitivity, fatigue, and qu …
Endogenous pain modulation in children with functional abdominal pain disorders.
Pas R, Rheel E, Van Oosterwijck S, Leysen L, Van De Vijver E, Nijs J, Ickmans K, Meeus M. Pas R, et al. Among authors: Leysen L. Pain. 2019 Aug;160(8):1883-1890. doi: 10.1097/j.pain.0000000000001566. Pain. 2019. PMID: 31335656
Conditioned pain modulation was recorded as an increase in the PPT at the trapezius test site in response to experimental conditioning pain imposed by the cold pressor task (12 ± 1°C). ...Parent-proxy and/or self-reported questionnaires were used to assess child's …
Conditioned pain modulation was recorded as an increase in the PPT at the trapezius test site in response to experimental conditionin …
Explaining pain following cancer: a practical guide for clinicians.
Nijs J, Wijma AJ, Leysen L, Pas R, Willaert W, Hoelen W, Ickmans K, Wilgen CPV. Nijs J, et al. Among authors: Leysen L. Braz J Phys Ther. 2019 Sep-Oct;23(5):367-377. doi: 10.1016/j.bjpt.2018.12.003. Epub 2018 Dec 21. Braz J Phys Ther. 2019. PMID: 30606621 Free PMC article. Review.
Therapists require an in-depth understanding of pain mechanisms, the skills to explain to their patients various pain mechanisms, specific communication skills (e.g. ...Its application is backed-up by mounting evidence supporting the effectiveness of PNE in non-canc …
Therapists require an in-depth understanding of pain mechanisms, the skills to explain to their patients various pain mechanis …
Chronic Pain in Breast Cancer Survivors: Nociceptive, Neuropathic, or Central Sensitization Pain?
Leysen L, Adriaenssens N, Nijs J, Pas R, Bilterys T, Vermeir S, Lahousse A, Beckwée D. Leysen L, et al. Pain Pract. 2019 Feb;19(2):183-195. doi: 10.1111/papr.12732. Epub 2018 Nov 15. Pain Pract. 2019. PMID: 30269431 Clinical Trial.
INTRODUCTION: The differentiation between acute and chronic pain can be insufficient for appropriate pain management. The aim of this study was to evaluate the prevalence of the predominant pain type (nociceptive, neuropathic, or central sensitization [CS] …
INTRODUCTION: The differentiation between acute and chronic pain can be insufficient for appropriate pain management. The aim …
Development and feasibility testing of a Pain Neuroscience Education program for children with chronic pain: treatment protocol.
Pas R, Meeus M, Malfliet A, Baert I, Oosterwijck SV, Leysen L, Nijs J, Ickmans K. Pas R, et al. Among authors: Leysen L. Braz J Phys Ther. 2018 May-Jun;22(3):248-253. doi: 10.1016/j.bjpt.2018.02.004. Epub 2018 Mar 4. Braz J Phys Ther. 2018. PMID: 29550259 Free PMC article.
BACKGROUND: Current treatment for adults with chronic pain often includes Pain Neuroscience Education (PNE) to make people understand the nature underlying their pain and thus provides a clear rational for a biopsychosocial approach. ...OBJECTIVES: The aim of …
BACKGROUND: Current treatment for adults with chronic pain often includes Pain Neuroscience Education (PNE) to make people und …
Sleep Disturbances in Chronic Pain: Neurobiology, Assessment, and Treatment in Physical Therapist Practice.
Nijs J, Mairesse O, Neu D, Leysen L, Danneels L, Cagnie B, Meeus M, Moens M, Ickmans K, Goubert D. Nijs J, et al. Among authors: Leysen L. Phys Ther. 2018 May 1;98(5):325-335. doi: 10.1093/ptj/pzy020. Phys Ther. 2018. PMID: 29425327 Review.
This review article applies the current understanding of insomnia to clinical practice, including assessment and conservative treatment of insomnia in people with chronic pain. Cognitive-behavioral therapy for insomnia can be efficacious for improvements in sleep initiatio …
This review article applies the current understanding of insomnia to clinical practice, including assessment and conservative treatment of i …
Hyperexcitability of the Central Nervous System in Children with Chronic Pain: A Systematic Review.
Pas R, Ickmans K, Van Oosterwijck S, Van der Cruyssen K, Foubert A, Leysen L, Nijs J, Meeus M. Pas R, et al. Among authors: Leysen L. Pain Med. 2018 Dec 1;19(12):2504-2514. doi: 10.1093/pm/pnx320. Pain Med. 2018. PMID: 29304243
OBJECTIVE: Hyperexcitability of the central nervous system plays an important role in the development and maintenance of chronic pain in adults. ...Preliminary evidence exists for altered cortical nociceptive processing in children with migraine and recurrent abdominal …
OBJECTIVE: Hyperexcitability of the central nervous system plays an important role in the development and maintenance of chronic pain
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