The IL-4Rα Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice.
Yang B, Wilkie H, Das M, Timilshina M, Bainter W, Woods B, Daya M, Boorgula MP, Mathias RA, Lai P, Petty CR, Weller E, Harb H, Chatila TA, Leung DYM, Beck LA, Simpson EL, Hata TR, Barnes KC, Phipatanakul W, Leyva-Castillo JM, Geha RS.
Yang B, et al. Among authors: leyva castillo jm.
J Allergy Clin Immunol. 2023 May;151(5):1296-1306.e7. doi: 10.1016/j.jaci.2023.01.011. Epub 2023 Jan 21.
J Allergy Clin Immunol. 2023.
PMID: 36690254