Li AP - Search Results

1

Human hepatocytes as an effective alternative experimental system for the evaluation of human drug properties: general concepts and assay procedures.

Li AP. Li AP. ALTEX. 2008;25(1):33-42. doi: 10.14573/altex.2008.1.33. ALTEX. 2008. PMID: 18360726

2

Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin.

Li AP, Jurima-Romet M. Li AP, et al. Cell Biol Toxicol. 1997 Jul;13(4-5):365-74. doi: 10.1023/a:1007451911843. Cell Biol Toxicol. 1997. PMID: 9298257

3

Primary hepatocyte cultures as an in vitro experimental model for the evaluation of pharmacokinetic drug-drug interactions.

Li AP. Li AP. Adv Pharmacol. 1997;43:103-30. doi: 10.1016/s1054-3589(08)60203-3. Adv Pharmacol. 1997. PMID: 9342174 Review. No abstract available.

4

Primary hepatocyte culture as an experimental model for the evaluation of interactions between xenobiotics and drug-metabolizing enzymes.

Li AP, Kedderis GL. Li AP, et al. Chem Biol Interact. 1997 Nov 6;107(1-2):1-3. doi: 10.1016/s0009-2797(97)00069-0. Chem Biol Interact. 1997. PMID: 9402945 No abstract available.

5

Preclinical evaluation of drug-drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction.

Li AP, Maurel P, Gomez-Lechon MJ, Cheng LC, Jurima-Romet M. Li AP, et al. Chem Biol Interact. 1997 Nov 6;107(1-2):5-16. doi: 10.1016/s0009-2797(97)00070-7. Chem Biol Interact. 1997. PMID: 9402946 Review.

6

An evaluation of the cytochrome P450 induction potential of pantoprazole in primary human hepatocytes.

Masubuchi N, Li AP, Okazaki O. Masubuchi N, et al. Among authors: li ap. Chem Biol Interact. 1998 Jul 3;114(1-2):1-13. doi: 10.1016/s0009-2797(98)00031-3. Chem Biol Interact. 1998. PMID: 9744552

7

Overview: hepatocytes and cryopreservation--a personal historical perspective.

Li AP. Li AP. Chem Biol Interact. 1999 Jun 1;121(1):1-5. doi: 10.1016/s0009-2797(99)00086-1. Chem Biol Interact. 1999. PMID: 10418966

8

Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential.

Li AP, Lu C, Brent JA, Pham C, Fackett A, Ruegg CE, Silber PM. Li AP, et al. Chem Biol Interact. 1999 Jun 1;121(1):17-35. doi: 10.1016/s0009-2797(99)00088-5. Chem Biol Interact. 1999. PMID: 10418968

9

Present status of the application of cryopreserved hepatocytes in the evaluation of xenobiotics: consensus of an international expert panel.

Li AP, Gorycki PD, Hengstler JG, Kedderis GL, Koebe HG, Rahmani R, de Sousas G, Silva JM, Skett P. Li AP, et al. Chem Biol Interact. 1999 Jun 1;121(1):117-23. doi: 10.1016/s0009-2797(99)00081-2. Chem Biol Interact. 1999. PMID: 10418974 Review.

10

Correlation between troglitazone cytotoxicity and drug metabolic enzyme activities in cryopreserved human hepatocytes.

Hewitt NJ, Lloyd S, Hayden M, Butler R, Sakai Y, Springer R, Fackett A, Li AP. Hewitt NJ, et al. Among authors: li ap. Chem Biol Interact. 2002 Nov 10;142(1-2):73-82. doi: 10.1016/s0009-2797(02)00055-8. Chem Biol Interact. 2002. PMID: 12399156

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