Li AP - Search Results

1

Primary human hepatocytes as a tool for the evaluation of structure-activity relationship in cytochrome P450 induction potential of xenobiotics: evaluation of rifampin, rifapentine and rifabutin.

Li AP, Reith MK, Rasmussen A, Gorski JC, Hall SD, Xu L, Kaminski DL, Cheng LK. Li AP, et al. Chem Biol Interact. 1997 Nov 6;107(1-2):17-30. doi: 10.1016/s0009-2797(97)00071-9. Chem Biol Interact. 1997. PMID: 9402947

2

2,3,7,8 Tetrachlorodibenzo-p-dioxin induction of cytochrome P4501A in cultured rat and human hepatocytes.

Xu L, Li AP, Kaminski DL, Ruh MF. Xu L, et al. Among authors: li ap. Chem Biol Interact. 2000 Feb 1;124(3):173-89. doi: 10.1016/s0009-2797(99)00149-0. Chem Biol Interact. 2000. PMID: 10728777

3

Rifampicin induction of lidocaine metabolism in cultured human hepatocytes.

Li AP, Rasmussen A, Xu L, Kaminski DL. Li AP, et al. J Pharmacol Exp Ther. 1995 Aug;274(2):673-7. J Pharmacol Exp Ther. 1995. PMID: 7636727

4

Substrates of human hepatic cytochrome P450 3A4.

Li AP, Kaminski DL, Rasmussen A. Li AP, et al. Toxicology. 1995 Dec 15;104(1-3):1-8. doi: 10.1016/0300-483x(95)03155-9. Toxicology. 1995. PMID: 8560487 Review.

5

Species comparison in P450 induction: effects of dexamethasone, omeprazole, and rifampin on P450 isoforms 1A and 3A in primary cultured hepatocytes from man, Sprague-Dawley rat, minipig, and beagle dog.

Lu C, Li AP. Lu C, et al. Among authors: li ap. Chem Biol Interact. 2001 May 16;134(3):271-81. doi: 10.1016/s0009-2797(01)00162-4. Chem Biol Interact. 2001. PMID: 11336975

6

Preclinical evaluation of drug-drug interaction potential: present status of the application of primary human hepatocytes in the evaluation of cytochrome P450 induction.

Li AP, Maurel P, Gomez-Lechon MJ, Cheng LC, Jurima-Romet M. Li AP, et al. Chem Biol Interact. 1997 Nov 6;107(1-2):5-16. doi: 10.1016/s0009-2797(97)00070-7. Chem Biol Interact. 1997. PMID: 9402946 Review.

7

Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential.

Li AP, Lu C, Brent JA, Pham C, Fackett A, Ruegg CE, Silber PM. Li AP, et al. Chem Biol Interact. 1999 Jun 1;121(1):17-35. doi: 10.1016/s0009-2797(99)00088-5. Chem Biol Interact. 1999. PMID: 10418968

8

Identification of glutathione conjugates of troglitazone in human hepatocytes.

Prabhu S, Fackett A, Lloyd S, McClellan HA, Terrell CM, Silber PM, Li AP. Prabhu S, et al. Among authors: li ap. Chem Biol Interact. 2002 Nov 10;142(1-2):83-97. doi: 10.1016/s0009-2797(02)00056-x. Chem Biol Interact. 2002. PMID: 12399157

9

Gene transfer in primary cultures of human hepatocytes.

Li AP, Myers CA, Kaminski DL. Li AP, et al. In Vitro Cell Dev Biol. 1992 May;28A(5):373-5. doi: 10.1007/BF02877062. In Vitro Cell Dev Biol. 1992. PMID: 1317838

10

A comparison of aroclor 1254-induced and uninduced rat liver microsomes to human liver microsomes in phenytoin O-deethylation, coumarin 7-hydroxylation, tolbutamide 4-hydroxylation, S-mephenytoin 4'-hydroxylation, chloroxazone 6-hydroxylation and testosterone 6beta-hydroxylation.

Easterbrook J, Fackett D, Li AP. Easterbrook J, et al. Among authors: li ap. Chem Biol Interact. 2001 May 16;134(3):243-9. doi: 10.1016/s0009-2797(01)00159-4. Chem Biol Interact. 2001. PMID: 11336973

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