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63,143 results
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Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling.
Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, Fu XD, Mills GB, Guan KL. Yu FX, et al. Among authors: Li H. Cell. 2012 Aug 17;150(4):780-91. doi: 10.1016/j.cell.2012.06.037. Epub 2012 Aug 2. Cell. 2012. PMID: 22863277 Free PMC article.
OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases.
Lu Y, Qu H, Qi D, Xu W, Liu S, Jin X, Song P, Guo Y, Jia Y, Wang X, Li H, Li Y, Quan C. Lu Y, et al. Among authors: Li H, Li Y. Stem Cell Res Ther. 2019 Jan 15;10(1):28. doi: 10.1186/s13287-018-1120-x. Stem Cell Res Ther. 2019. PMID: 30646941 Free PMC article.
Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription.
Xiao R, Chen JY, Liang Z, Luo D, Chen G, Lu ZJ, Chen Y, Zhou B, Li H, Du X, Yang Y, San M, Wei X, Liu W, Lécuyer E, Graveley BR, Yeo GW, Burge CB, Zhang MQ, Zhou Y, Fu XD. Xiao R, et al. Among authors: Li H. Cell. 2019 Jun 27;178(1):107-121.e18. doi: 10.1016/j.cell.2019.06.001. Cell. 2019. PMID: 31251911 Free PMC article.
The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations.
Chen L, Chen JY, Huang YJ, Gu Y, Qiu J, Qian H, Shao C, Zhang X, Hu J, Li H, He S, Zhou Y, Abdel-Wahab O, Zhang DE, Fu XD. Chen L, et al. Among authors: Li H. Mol Cell. 2018 Feb 1;69(3):412-425.e6. doi: 10.1016/j.molcel.2017.12.029. Epub 2018 Jan 27. Mol Cell. 2018. PMID: 29395063 Free PMC article.
Enhanced R-loops are linked to compromised proliferation of bone-marrow-derived blood progenitors, which can be partially rescued by RNase H overexpression, suggesting a direct contribution of augmented R-loops to the MDS phenotype....
Enhanced R-loops are linked to compromised proliferation of bone-marrow-derived blood progenitors, which can be partially rescued by RNase …
R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters.
Chen L, Chen JY, Zhang X, Gu Y, Xiao R, Shao C, Tang P, Qian H, Luo D, Li H, Zhou Y, Zhang DE, Fu XD. Chen L, et al. Among authors: Li H. Mol Cell. 2017 Nov 16;68(4):745-757.e5. doi: 10.1016/j.molcel.2017.10.008. Epub 2017 Nov 2. Mol Cell. 2017. PMID: 29104020 Free PMC article.
To enable precision analysis of R-loops in vivo, we develop an RNase-H-based approach; this reveals predominant R-loop formation near gene promoters with strong G/C skew and propensity to form G-quadruplex in non-template DNA, corroborating with all biochemically established properties of R-loops. ...
To enable precision analysis of R-loops in vivo, we develop an RNase-H-based approach; this reveals predominant R-loop formation near …
Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis.
Gou LT, Dai P, Yang JH, Xue Y, Hu YP, Zhou Y, Kang JY, Wang X, Li H, Hua MM, Zhao S, Hu SD, Wu LG, Shi HJ, Li Y, Fu XD, Qu LH, Wang ED, Liu MF. Gou LT, et al. Among authors: Li H, Li Y. Cell Res. 2014 Jun;24(6):680-700. doi: 10.1038/cr.2014.41. Epub 2014 May 2. Cell Res. 2014. PMID: 24787618 Free PMC article.
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