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Engineered bi-histidine metal chelation sites map the structure of the mechanical unfolding transition state of an elastomeric protein domain GB1.
Shen T, Cao Y, Zhuang S, Li H. Shen T, et al. Among authors: li h. Biophys J. 2012 Aug 22;103(4):807-16. doi: 10.1016/j.bpj.2012.07.019. Biophys J. 2012. PMID: 22947942 Free PMC article.
The mechanical stability of ubiquitin is linkage dependent.
Carrion-Vazquez M, Li H, Lu H, Marszalek PE, Oberhauser AF, Fernandez JM. Carrion-Vazquez M, et al. Among authors: li h. Nat Struct Biol. 2003 Sep;10(9):738-43. doi: 10.1038/nsb965. Epub 2003 Aug 17. Nat Struct Biol. 2003. PMID: 12923571
The force-driven conformations of heparin studied with single molecule force microscopy.
Marszalek PE, Oberhauser AF, Li H, Fernandez JM. Marszalek PE, et al. Among authors: li h. Biophys J. 2003 Oct;85(4):2696-704. doi: 10.1016/S0006-3495(03)74692-X. Biophys J. 2003. PMID: 14507732 Free PMC article.
Mechanical design of the first proximal Ig domain of human cardiac titin revealed by single molecule force spectroscopy.
Li H, Fernandez JM. Li H, et al. J Mol Biol. 2003 Nov 14;334(1):75-86. doi: 10.1016/j.jmb.2003.09.036. J Mol Biol. 2003. PMID: 14596801
Force-clamp spectroscopy monitors the folding trajectory of a single protein.
Fernandez JM, Li H. Fernandez JM, et al. Among authors: li h. Science. 2004 Mar 12;303(5664):1674-8. doi: 10.1126/science.1092497. Science. 2004. PMID: 15017000
Nonmechanical protein can have significant mechanical stability.
Cao Y, Lam C, Wang M, Li H. Cao Y, et al. Among authors: li h. Angew Chem Int Ed Engl. 2006 Jan 16;45(4):642-5. doi: 10.1002/anie.200502623. Angew Chem Int Ed Engl. 2006. PMID: 16345105 No abstract available.
Sub-angstrom conformational changes of a single molecule captured by AFM variance analysis.
Walther KA, Brujić J, Li H, Fernández JM. Walther KA, et al. Among authors: li h. Biophys J. 2006 May 15;90(10):3806-12. doi: 10.1529/biophysj.105.076224. Epub 2006 Feb 24. Biophys J. 2006. PMID: 16500987 Free PMC article.
Single molecule force spectroscopy reveals a weakly populated microstate of the FnIII domains of tenascin.
Cao Y, Li H. Cao Y, et al. Among authors: li h. J Mol Biol. 2006 Aug 11;361(2):372-81. doi: 10.1016/j.jmb.2006.06.014. Epub 2006 Jun 27. J Mol Biol. 2006. PMID: 16842818
Engineering proteins with novel mechanical properties by recombination of protein fragments.
Sharma D, Cao Y, Li H. Sharma D, et al. Among authors: li h. Angew Chem Int Ed Engl. 2006 Aug 25;45(34):5633-8. doi: 10.1002/anie.200600382. Angew Chem Int Ed Engl. 2006. PMID: 16856192 No abstract available.
Contour length and refolding rate of a small protein controlled by engineered disulfide bonds.
Ainavarapu SR, Brujic J, Huang HH, Wiita AP, Lu H, Li L, Walther KA, Carrion-Vazquez M, Li H, Fernandez JM. Ainavarapu SR, et al. Among authors: li l, li h. Biophys J. 2007 Jan 1;92(1):225-33. doi: 10.1529/biophysj.106.091561. Epub 2006 Oct 6. Biophys J. 2007. PMID: 17028145 Free PMC article.
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