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Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.
Zhang W, Li J, Suzuki K, Qu J, Wang P, Zhou J, Liu X, Ren R, Xu X, Ocampo A, Yuan T, Yang J, Li Y, Shi L, Guan D, Pan H, Duan S, Ding Z, Li M, Yi F, Bai R, Wang Y, Chen C, Yang F, Li X, Wang Z, Aizawa E, Goebl A, Soligalla RD, Reddy P, Esteban CR, Tang F, Liu GH, Belmonte JC. Zhang W, et al. Among authors: li y, li j, li x, li m. Science. 2015 Jun 5;348(6239):1160-3. doi: 10.1126/science.aaa1356. Epub 2015 Apr 30. Science. 2015. PMID: 25931448 Free PMC article.
PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype.
Duan S, Yuan G, Liu X, Ren R, Li J, Zhang W, Wu J, Xu X, Fu L, Li Y, Yang J, Zhang W, Bai R, Yi F, Suzuki K, Gao H, Esteban CR, Zhang C, Izpisua Belmonte JC, Chen Z, Wang X, Jiang T, Qu J, Tang F, Liu GH. Duan S, et al. Among authors: li y, li j. Nat Commun. 2015 Dec 3;6:10068. doi: 10.1038/ncomms10068. Nat Commun. 2015. PMID: 26632666 Free PMC article.
SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2.
Pan H, Guan D, Liu X, Li J, Wang L, Wu J, Zhou J, Zhang W, Ren R, Zhang W, Li Y, Yang J, Hao Y, Yuan T, Yuan G, Wang H, Ju Z, Mao Z, Li J, Qu J, Tang F, Liu GH. Pan H, et al. Among authors: li y, li j. Cell Res. 2016 Feb;26(2):190-205. doi: 10.1038/cr.2016.4. Epub 2016 Jan 15. Cell Res. 2016. PMID: 26768768 Free PMC article.
Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis.
Deng L, Ren R, Liu Z, Song M, Li J, Wu Z, Ren X, Fu L, Li W, Zhang W, Guillen P, Izpisua Belmonte JC, Chan P, Qu J, Liu GH. Deng L, et al. Among authors: li j, li w. Nat Commun. 2019 Jul 26;10(1):3329. doi: 10.1038/s41467-019-10831-8. Nat Commun. 2019. PMID: 31350386 Free PMC article.
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