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A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway.
Pang T, Wang YJ, Gao YX, Xu Y, Li Q, Zhou YB, Xu L, Huang ZJ, Liao H, Zhang LY, Gao JR, Ye Q, Li J. Pang T, et al. Acta Pharmacol Sin. 2016 Jun;37(6):741-52. doi: 10.1038/aps.2016.3. Epub 2016 Apr 25. Acta Pharmacol Sin. 2016. PMID: 27108601 Free PMC article.
A Jak2-selective inhibitor potently reverses the immune suppression by modulating the tumor microenvironment for cancer immunotherapy.
He W, Zhu Y, Mu R, Xu J, Zhang X, Wang C, Li Q, Huang Z, Zhang J, Pan Y, Han J, Dong L. He W, et al. Biochem Pharmacol. 2017 Dec 1;145:132-146. doi: 10.1016/j.bcp.2017.08.019. Epub 2017 Aug 30. Biochem Pharmacol. 2017. PMID: 28859967
Kaempferol-3-O-glucorhamnoside inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo.
Sun Z, Li Q, Hou R, Sun H, Tang Q, Wang H, Hao Z, Kang S, Xu T, Wu S. Sun Z, et al. Toxicol Appl Pharmacol. 2019 Feb 1;364:22-28. doi: 10.1016/j.taap.2018.12.008. Epub 2018 Dec 7. Toxicol Appl Pharmacol. 2019. PMID: 30528763
Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: Design of a glucomannan coating material.
Niu Y, Li Q, Xie R, Liu S, Wang R, Xing P, Shi Y, Wang Y, Dong L, Wang C. Niu Y, et al. Biomaterials. 2017 Sep;139:39-55. doi: 10.1016/j.biomaterials.2017.05.042. Epub 2017 May 24. Biomaterials. 2017. PMID: 28582717
Producing anti-inflammatory macrophages by nanoparticle-triggered clustering of mannose receptors.
Gan J, Dou Y, Li Y, Wang Z, Wang L, Liu S, Li Q, Yu H, Liu C, Han C, Huang Z, Zhang J, Wang C, Dong L. Gan J, et al. Biomaterials. 2018 Sep;178:95-108. doi: 10.1016/j.biomaterials.2018.06.015. Epub 2018 Jun 14. Biomaterials. 2018. PMID: 29920405
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