Li RA - Search Results

1

Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells.

Li RA, Keung W, Cashman TJ, Backeris PC, Johnson BV, Bardot ES, Wong AOT, Chan PKW, Chan CWY, Costa KD. Li RA, et al. Biomaterials. 2018 May;163:116-127. doi: 10.1016/j.biomaterials.2018.02.024. Epub 2018 Feb 10. Biomaterials. 2018. PMID: 29459321 Free PMC article.

2

Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias.

Wang J, Chen A, Lieu DK, Karakikes I, Chen G, Keung W, Chan CW, Hajjar RJ, Costa KD, Khine M, Li RA. Wang J, et al. Among authors: li ra. Biomaterials. 2013 Nov;34(35):8878-86. doi: 10.1016/j.biomaterials.2013.07.039. Epub 2013 Aug 12. Biomaterials. 2013. PMID: 23942210

3

Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs.

Chen G, Li S, Karakikes I, Ren L, Chow MZ, Chopra A, Keung W, Yan B, Chan CW, Costa KD, Kong CW, Hajjar RJ, Chen CS, Li RA. Chen G, et al. Among authors: li ra, li s. Circ Arrhythm Electrophysiol. 2015 Feb;8(1):193-202. doi: 10.1161/CIRCEP.114.002049. Epub 2014 Dec 10. Circ Arrhythm Electrophysiol. 2015. PMID: 25504561 Free PMC article.

4

Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy.

Cashman TJ, Josowitz R, Gelb BD, Li RA, Dubois NC, Costa KD. Cashman TJ, et al. Among authors: li ra. J Vis Exp. 2016 Mar 1;(109):e53447. doi: 10.3791/53447. J Vis Exp. 2016. PMID: 26967678 Free PMC article.

5

A Micropatterned Human Pluripotent Stem Cell-Based Ventricular Cardiac Anisotropic Sheet for Visualizing Drug-Induced Arrhythmogenicity.

Shum AM, Che H, Wong AO, Zhang C, Wu H, Chan CW, Costa K, Khine M, Kong CW, Li RA. Shum AM, et al. Among authors: li ra. Adv Mater. 2017 Jan;29(1). doi: 10.1002/adma.201602448. Epub 2016 Nov 2. Adv Mater. 2017. PMID: 27805726

6

AAV-mediated conversion of human pluripotent stem cell-derived pacemaker.

Chan PKW, Geng L, Gao Y, Keung W, Li RA. Chan PKW, et al. Among authors: li ra. Biochem Biophys Res Commun. 2017 Dec 9;494(1-2):346-351. doi: 10.1016/j.bbrc.2017.10.023. Epub 2017 Oct 6. Biochem Biophys Res Commun. 2017. PMID: 28989025

7

Machine Learning of Human Pluripotent Stem Cell-Derived Engineered Cardiac Tissue Contractility for Automated Drug Classification.

Lee EK, Tran DD, Keung W, Chan P, Wong G, Chan CW, Costa KD, Li RA, Khine M. Lee EK, et al. Among authors: li ra. Stem Cell Reports. 2017 Nov 14;9(5):1560-1572. doi: 10.1016/j.stemcr.2017.09.008. Epub 2017 Oct 12. Stem Cell Reports. 2017. PMID: 29033305 Free PMC article.

8

Probing flecainide block of I_Na using human pluripotent stem cell-derived ventricular cardiomyocytes adapted to automated patch-clamping and 2D monolayers.

Geng L, Kong CW, Wong AOT, Shum AM, Chow MZY, Che H, Zhang C, Yau KL, Chan CW, Keung W, Li RA. Geng L, et al. Among authors: li ra. Toxicol Lett. 2018 Sep 15;294:61-72. doi: 10.1016/j.toxlet.2018.05.006. Epub 2018 May 21. Toxicol Lett. 2018. PMID: 29758359

9

Human Cardiac Ventricular-Like Organoid Chambers and Tissue Strips From Pluripotent Stem Cells as a Two-Tiered Assay for Inotropic Responses.

Keung W, Chan PKW, Backeris PC, Lee EK, Wong N, Wong AOT, Wong GKY, Chan CWY, Fermini B, Costa KD, Li RA. Keung W, et al. Among authors: li ra. Clin Pharmacol Ther. 2019 Aug;106(2):402-414. doi: 10.1002/cpt.1385. Epub 2019 Mar 28. Clin Pharmacol Ther. 2019. PMID: 30723889

10

Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues.

Chow MZ, Sadrian SN, Keung W, Geng L, Ren L, Kong CW, Wong AO, Hulot JS, Chen CS, Costa KD, Hajjar RJ, Li RA. Chow MZ, et al. Among authors: li ra. Sci Rep. 2019 May 16;9(1):7502. doi: 10.1038/s41598-019-42953-w. Sci Rep. 2019. PMID: 31097748 Free PMC article.

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