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101,459 results
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Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability.
Li X, Manley JL. Li X, et al. Cell. 2005 Aug 12;122(3):365-78. doi: 10.1016/j.cell.2005.06.008. Cell. 2005. PMID: 16096057
R-loop-mediated genomic instability is caused by impairment of replication fork progression.
Gan W, Guan Z, Liu J, Gui T, Shen K, Manley JL, Li X. Gan W, et al. Among authors: li x. Genes Dev. 2011 Oct 1;25(19):2041-56. doi: 10.1101/gad.17010011. Genes Dev. 2011. PMID: 21979917 Free PMC article.
The RNA binding protein RNPS1 alleviates ASF/SF2 depletion-induced genomic instability.
Li X, Niu T, Manley JL. Li X, et al. RNA. 2007 Dec;13(12):2108-15. doi: 10.1261/rna.734407. Epub 2007 Oct 24. RNA. 2007. PMID: 17959926 Free PMC article.
Cotranscriptional processes and their influence on genome stability.
Li X, Manley JL. Li X, et al. Genes Dev. 2006 Jul 15;20(14):1838-47. doi: 10.1101/gad.1438306. Genes Dev. 2006. PMID: 16847344 Review.
Alternative splicing and control of apoptotic DNA fragmentation.
Li X, Manley JL. Li X, et al. Cell Cycle. 2006 Jun;5(12):1286-8. doi: 10.4161/cc.5.12.2832. Epub 2006 Jun 15. Cell Cycle. 2006. PMID: 16760667
New talents for an old acquaintance: the SR protein splicing factor ASF/SF2 functions in the maintenance of genome stability.
Li X, Manley JL. Li X, et al. Cell Cycle. 2005 Dec;4(12):1706-8. doi: 10.4161/cc.4.12.2210. Epub 2005 Dec 27. Cell Cycle. 2005. PMID: 16294036
Loss of splicing factor ASF/SF2 induces G2 cell cycle arrest and apoptosis, but inhibits internucleosomal DNA fragmentation.
Li X, Wang J, Manley JL. Li X, et al. Genes Dev. 2005 Nov 15;19(22):2705-14. doi: 10.1101/gad.1359305. Epub 2005 Oct 31. Genes Dev. 2005. PMID: 16260492 Free PMC article.
RBM5 promotes exon 4 skipping of AID pre-mRNA by competing with the binding of U2AF65 to the polypyrimidine tract.
Jin W, Niu Z, Xu D, Li X. Jin W, et al. Among authors: li x. FEBS Lett. 2012 Nov 2;586(21):3852-7. doi: 10.1016/j.febslet.2012.09.006. Epub 2012 Sep 24. FEBS Lett. 2012. PMID: 23017209
Activation-induced cytidine deaminase (AID)-dependent somatic hypermutation requires a splice isoform of the serine/arginine-rich (SR) protein SRSF1.
Kanehiro Y, Todo K, Negishi M, Fukuoka J, Gan W, Hikasa T, Kaga Y, Takemoto M, Magari M, Li X, Manley JL, Ohmori H, Kanayama N. Kanehiro Y, et al. Among authors: li x. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1216-21. doi: 10.1073/pnas.1120368109. Epub 2012 Jan 9. Proc Natl Acad Sci U S A. 2012. PMID: 22232677 Free PMC article.
Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity.
Niu Z, Jin W, Zhang L, Li X. Niu Z, et al. Among authors: li x. FEBS Lett. 2012 Apr 5;586(7):977-83. doi: 10.1016/j.febslet.2012.02.052. Epub 2012 Mar 8. FEBS Lett. 2012. PMID: 22569250
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