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130,327 results
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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.
Inoki K, Li Y, Zhu T, Wu J, Guan KL. Inoki K, et al. Among authors: li y. Nat Cell Biol. 2002 Sep;4(9):648-57. doi: 10.1038/ncb839. Nat Cell Biol. 2002. PMID: 12172553
UV irradiation induces Snail expression by AP-1 dependent mechanism in human skin keratinocytes.
Li Y, Liu Y, Xu Y, Voorhees JJ, Fisher GJ. Li Y, et al. J Dermatol Sci. 2010 Nov;60(2):105-13. doi: 10.1016/j.jdermsci.2010.08.003. Epub 2010 Aug 26. J Dermatol Sci. 2010. PMID: 20851575
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression.
Yu J, Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, Wang X, Wu L, Li J, Hu M, Gong Y, Cheng H, Laxman B, Vellaichamy A, Shankar S, Li Y, Dhanasekaran SM, Morey R, Barrette T, Lonigro RJ, Tomlins SA, Varambally S, Qin ZS, Chinnaiyan AM. Yu J, et al. Among authors: li j, li y. Cancer Cell. 2010 May 18;17(5):443-54. doi: 10.1016/j.ccr.2010.03.018. Cancer Cell. 2010. PMID: 20478527 Free PMC article.
Differential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skin.
RittiƩ L, Kansra S, Stoll SW, Li Y, Gudjonsson JE, Shao Y, Michael LE, Fisher GJ, Johnson TM, Elder JT. RittiƩ L, et al. Among authors: li y. Am J Pathol. 2007 Jun;170(6):2089-99. doi: 10.2353/ajpath.2007.060537. Am J Pathol. 2007. PMID: 17525275 Free PMC article.
Measurements of TSC2 GAP activity toward Rheb.
Li Y, Inoki K, Vikis H, Guan KL. Li Y, et al. Methods Enzymol. 2006;407:46-54. doi: 10.1016/S0076-6879(05)07005-9. Methods Enzymol. 2006. PMID: 16757313
Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb.
Li Y, Wang Y, Kim E, Beemiller P, Wang CY, Swanson J, You M, Guan KL. Li Y, et al. J Biol Chem. 2007 Dec 7;282(49):35803-13. doi: 10.1074/jbc.M705231200. Epub 2007 Oct 10. J Biol Chem. 2007. PMID: 17928295
TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.
Chong-Kopera H, Inoki K, Li Y, Zhu T, Garcia-Gonzalo FR, Rosa JL, Guan KL. Chong-Kopera H, et al. Among authors: li y. J Biol Chem. 2006 Mar 31;281(13):8313-6. doi: 10.1074/jbc.C500451200. Epub 2006 Feb 7. J Biol Chem. 2006. PMID: 16464865
Signaling by target of rapamycin proteins in cell growth control.
Inoki K, Ouyang H, Li Y, Guan KL. Inoki K, et al. Among authors: li y. Microbiol Mol Biol Rev. 2005 Mar;69(1):79-100. doi: 10.1128/MMBR.69.1.79-100.2005. Microbiol Mol Biol Rev. 2005. PMID: 15755954 Free PMC article. Review.
Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity.
Li Y, Inoki K, Guan KL. Li Y, et al. Mol Cell Biol. 2004 Sep;24(18):7965-75. doi: 10.1128/MCB.24.18.7965-7975.2004. Mol Cell Biol. 2004. PMID: 15340059 Free PMC article.
TSC2: filling the GAP in the mTOR signaling pathway.
Li Y, Corradetti MN, Inoki K, Guan KL. Li Y, et al. Trends Biochem Sci. 2004 Jan;29(1):32-8. doi: 10.1016/j.tibs.2003.11.007. Trends Biochem Sci. 2004. PMID: 14729330 Review.
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