Li Y - Search Results

1

Productivity and quality improvement for a symmetric bispecific antibody through the application of intensified perfusion cell culture.

Qin Y, Ma R, Li Y, Li Y, Chen G, Zhou W. Qin Y, et al. Among authors: li y. Antib Ther. 2022 May 3;5(2):111-120. doi: 10.1093/abt/tbac009. eCollection 2022 Apr. Antib Ther. 2022. PMID: 35719210 Free PMC article.

2

Developability assessment at early-stage discovery to enable development of antibody-derived therapeutics.

Zhang W, Wang H, Feng N, Li Y, Gu J, Wang Z. Zhang W, et al. Among authors: li y. Antib Ther. 2022 Nov 11;6(1):13-29. doi: 10.1093/abt/tbac029. eCollection 2023 Jan. Antib Ther. 2022. PMID: 36683767 Free PMC article. Review.

3

A brief introduction of IgG-like bispecific antibody purification: Methods for removing product-related impurities.

Li Y. Li Y. Protein Expr Purif. 2019 Mar;155:112-119. doi: 10.1016/j.pep.2018.11.011. Epub 2018 Dec 1. Protein Expr Purif. 2019. PMID: 30513344 Review.

4

Monitoring removal of hole-hole homodimer by analytical hydrophobic interaction chromatography in purifying a bispecific antibody.

Chen T, Han J, Guo G, Wang Q, Wang Y, Li Y. Chen T, et al. Among authors: li y. Protein Expr Purif. 2019 Dec;164:105457. doi: 10.1016/j.pep.2019.105457. Epub 2019 Jul 23. Protein Expr Purif. 2019. PMID: 31344474

5

Removal of half antibody, hole-hole homodimer and aggregates during bispecific antibody purification using MMC ImpRes mixed-mode chromatography.

Tang J, Zhang X, Chen T, Wang Y, Li Y. Tang J, et al. Among authors: li y. Protein Expr Purif. 2020 Mar;167:105529. doi: 10.1016/j.pep.2019.105529. Epub 2019 Nov 4. Protein Expr Purif. 2020. PMID: 31698035

6

Removing half antibody byproduct by Protein A chromatography during the purification of a bispecific antibody.

Chen X, Wang Y, Li Y. Chen X, et al. Among authors: li y. Protein Expr Purif. 2020 Aug;172:105635. doi: 10.1016/j.pep.2020.105635. Epub 2020 Apr 5. Protein Expr Purif. 2020. PMID: 32268171

7

A potential downstream platform approach for WuXiBody-based IgG-like bispecific antibodies.

Guo G, Han J, Wang Y, Li Y. Guo G, et al. Among authors: li y. Protein Expr Purif. 2020 Sep;173:105647. doi: 10.1016/j.pep.2020.105647. Epub 2020 Apr 23. Protein Expr Purif. 2020. PMID: 32334139

8

Protein L chromatography: A useful tool for monitoring/separating homodimers during the purification of IgG-like asymmetric bispecific antibodies.

Chen X, Wang Y, Wang Y, Li Y. Chen X, et al. Among authors: li y. Protein Expr Purif. 2020 Nov;175:105711. doi: 10.1016/j.pep.2020.105711. Epub 2020 Jul 29. Protein Expr Purif. 2020. PMID: 32738435

9

Removing a difficult-to-separate byproduct by Capto L affinity chromatography during the purification of a WuXiBody-based bispecific antibody.

Wang Y, Chen X, Wang Y, Li Y. Wang Y, et al. Among authors: li y. Protein Expr Purif. 2020 Nov;175:105713. doi: 10.1016/j.pep.2020.105713. Epub 2020 Jul 29. Protein Expr Purif. 2020. PMID: 32738439

10

Removing light chain-missing byproducts and aggregates by Capto MMC ImpRes mixed-mode chromatography during the purification of two WuXiBody-based bispecific antibodies.

Wan Y, Zhang T, Wang Y, Wang Y, Li Y. Wan Y, et al. Among authors: li y. Protein Expr Purif. 2020 Nov;175:105712. doi: 10.1016/j.pep.2020.105712. Epub 2020 Jul 29. Protein Expr Purif. 2020. PMID: 32738441

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