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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy.
Fang Y, McGrail DJ, Sun C, Labrie M, Chen X, Zhang D, Ju Z, Vellano CP, Lu Y, Li Y, Jeong KJ, Ding Z, Liang J, Wang SW, Dai H, Lee S, Sahni N, Mercado-Uribe I, Kim TB, Chen K, Lin SY, Peng G, Westin SN, Liu J, O'Connor MJ, Yap TA, Mills GB. Fang Y, et al. Among authors: liang j. Cancer Cell. 2019 Jun 10;35(6):851-867.e7. doi: 10.1016/j.ccell.2019.05.001. Cancer Cell. 2019. PMID: 31185210 Free PMC article.
BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer.
Rai R, Dai H, Multani AS, Li K, Chin K, Gray J, Lahad JP, Liang J, Mills GB, Meric-Bernstam F, Lin SY. Rai R, et al. Among authors: liang j. Cancer Cell. 2006 Aug;10(2):145-57. doi: 10.1016/j.ccr.2006.07.002. Epub 2006 Jul 27. Cancer Cell. 2006. PMID: 16872911 Free PMC article.
Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models.
Cheong JH, Park ES, Liang J, Dennison JB, Tsavachidou D, Nguyen-Charles C, Wa Cheng K, Hall H, Zhang D, Lu Y, Ravoori M, Kundra V, Ajani J, Lee JS, Ki Hong W, Mills GB. Cheong JH, et al. Among authors: liang j. Mol Cancer Ther. 2011 Dec;10(12):2350-62. doi: 10.1158/1535-7163.MCT-11-0497. Epub 2011 Oct 12. Mol Cancer Ther. 2011. PMID: 21992792 Free PMC article.
Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520.
Park YY, Kim SB, Han HD, Sohn BH, Kim JH, Liang J, Lu Y, Rodriguez-Aguayo C, Lopez-Berestein G, Mills GB, Sood AK, Lee JS. Park YY, et al. Among authors: liang j. Hepatology. 2013 Jul;58(1):182-91. doi: 10.1002/hep.26310. Epub 2013 May 15. Hepatology. 2013. PMID: 23389994 Free PMC article.
AMPK: a contextual oncogene or tumor suppressor?
Liang J, Mills GB. Liang J, et al. Cancer Res. 2013 May 15;73(10):2929-35. doi: 10.1158/0008-5472.CAN-12-3876. Epub 2013 May 3. Cancer Res. 2013. PMID: 23644529 Free PMC article. Review.
Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation.
Zhou G, Wang J, Zhao M, Xie TX, Tanaka N, Sano D, Patel AA, Ward AM, Sandulache VC, Jasser SA, Skinner HD, Fitzgerald AL, Osman AA, Wei Y, Xia X, Songyang Z, Mills GB, Hung MC, Caulin C, Liang J, Myers JN. Zhou G, et al. Among authors: liang j. Mol Cell. 2014 Jun 19;54(6):960-974. doi: 10.1016/j.molcel.2014.04.024. Epub 2014 May 22. Mol Cell. 2014. PMID: 24857548 Free PMC article.
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