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15,326 results

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Massively targeted evaluation of therapeutic CRISPR off-targets in cells.
Pan X, Qu K, Yuan H, Xiang X, Anthon C, Pashkova L, Liang X, Han P, Corsi GI, Xu F, Liu P, Zhong J, Zhou Y, Ma T, Jiang H, Liu J, Wang J, Jessen N, Bolund L, Yang H, Xu X, Church GM, Gorodkin J, Lin L, Luo Y. Pan X, et al. Among authors: liang x. Nat Commun. 2022 Jul 13;13(1):4049. doi: 10.1038/s41467-022-31543-6. Nat Commun. 2022. PMID: 35831290 Free PMC article.
LION: a simple and rapid method to achieve CRISPR gene editing.
Xiang X, Luo L, Nodzyński M, Li C, Han P, Dou H, Petersen TS, Liang X, Pan X, Qu K, Yang L, Dang Y, Liu X, Bolund L, Zhang X, Tong G, Xing Y, Luo Y, Lin L. Xiang X, et al. Among authors: liang x. Cell Mol Life Sci. 2019 Jul;76(13):2633-2645. doi: 10.1007/s00018-019-03064-x. Epub 2019 Mar 18. Cell Mol Life Sci. 2019. PMID: 30887099
Efficient correction of Duchenne muscular dystrophy mutations by SpCas9 and dual gRNAs.
Xiang X, Zhao X, Pan X, Dong Z, Yu J, Li S, Liang X, Han P, Qu K, Jensen JB, Farup J, Wang F, Petersen TS, Bolund L, Teng H, Lin L, Luo Y. Xiang X, et al. Among authors: liang x. Mol Ther Nucleic Acids. 2021 Mar 13;24:403-415. doi: 10.1016/j.omtn.2021.03.005. eCollection 2021 Jun 4. Mol Ther Nucleic Acids. 2021. PMID: 33868784 Free PMC article.
Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning.
Xiang X, Corsi GI, Anthon C, Qu K, Pan X, Liang X, Han P, Dong Z, Liu L, Zhong J, Ma T, Wang J, Zhang X, Jiang H, Xu F, Liu X, Xu X, Wang J, Yang H, Bolund L, Church GM, Lin L, Gorodkin J, Luo Y. Xiang X, et al. Among authors: liang x. Nat Commun. 2021 May 28;12(1):3238. doi: 10.1038/s41467-021-23576-0. Nat Commun. 2021. PMID: 34050182 Free PMC article.
Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level.
Wang F, Ding P, Liang X, Ding X, Brandt CB, Sjöstedt E, Zhu J, Bolund S, Zhang L, de Rooij LPMH, Luo L, Wei Y, Zhao W, Lv Z, Haskó J, Li R, Qin Q, Jia Y, Wu W, Yuan Y, Pu M, Wang H, Wu A, Xie L, Liu P, Chen F, Herold J, Kalucka J, Karlsson M, Zhang X, Helmig RB, Fagerberg L, Lindskog C, Pontén F, Uhlen M, Bolund L, Jessen N, Jiang H, Xu X, Yang H, Carmeliet P, Mulder J, Chen D, Lin L, Luo Y. Wang F, et al. Among authors: liang x. Nat Commun. 2022 Jun 24;13(1):3620. doi: 10.1038/s41467-022-31388-z. Nat Commun. 2022. PMID: 35750885 Free PMC article.
Vasculogenesis in kidney organoids upon transplantation.
Koning M, Dumas SJ, Avramut MC, Koning RI, Meta E, Lievers E, Wiersma LE, Borri M, Liang X, Xie L, Liu P, Chen F, Lin L, Luo Y, Mulder J, Spijker HS, Jaffredo T, van den Berg BM, Carmeliet P, van den Berg CW, Rabelink TJ. Koning M, et al. Among authors: liang x. NPJ Regen Med. 2022 Aug 19;7(1):40. doi: 10.1038/s41536-022-00237-4. NPJ Regen Med. 2022. PMID: 35986027 Free PMC article.
Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level.
Wang F, Ding P, Liang X, Ding X, Brandt CB, Sjöstedt E, Zhu J, Bolund S, Zhang L, de Rooij LPMH, Luo L, Wei Y, Zhao W, Lv Z, Haskó J, Li R, Qin Q, Jia Y, Wu W, Yuan Y, Pu M, Wang H, Wu A, Xie L, Liu P, Chen F, Herold J, Kalucka J, Karlsson M, Zhang X, Helmig RB, Fagerberg L, Lindskog C, Pontén F, Uhlen M, Bolund L, Jessen N, Jiang H, Xu X, Yang H, Carmeliet P, Mulder J, Chen D, Lin L, Luo Y. Wang F, et al. Among authors: liang x. Nat Commun. 2022 Nov 8;13(1):6748. doi: 10.1038/s41467-022-34498-w. Nat Commun. 2022. PMID: 36347857 Free PMC article. No abstract available.
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