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Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway.
Shi J, Guan J, Jiang B, Brenner DA, Del Monte F, Ward JE, Connors LH, Sawyer DB, Semigran MJ, Macgillivray TE, Seldin DC, Falk R, Liao R. Shi J, et al. Among authors: liao r. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4188-93. doi: 10.1073/pnas.0912263107. Epub 2010 Feb 11. Proc Natl Acad Sci U S A. 2010. PMID: 20150510 Free PMC article.
Current perspectives on cardiac amyloidosis.
Guan J, Mishra S, Falk RH, Liao R. Guan J, et al. Among authors: liao r. Am J Physiol Heart Circ Physiol. 2012 Feb 1;302(3):H544-52. doi: 10.1152/ajpheart.00815.2011. Epub 2011 Nov 4. Am J Physiol Heart Circ Physiol. 2012. PMID: 22058156 Free PMC article. Review.
Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity.
Guan J, Mishra S, Shi J, Plovie E, Qiu Y, Cao X, Gianni D, Jiang B, Del Monte F, Connors LH, Seldin DC, Lavatelli F, Rognoni P, Palladini G, Merlini G, Falk RH, Semigran MJ, Dec GW Jr, Macrae CA, Liao R. Guan J, et al. Among authors: liao r. Basic Res Cardiol. 2013 Sep;108(5):378. doi: 10.1007/s00395-013-0378-5. Epub 2013 Aug 28. Basic Res Cardiol. 2013. PMID: 23982491 Free PMC article.
Amyloid Cardiomyopathy: Disease on the Rise.
Liao R, Ward JE. Liao R, et al. Circ Res. 2017 Jun 9;120(12):1865-1867. doi: 10.1161/CIRCRESAHA.117.310643. Circ Res. 2017. PMID: 28596171 Free PMC article. Review. No abstract available.
Zebrafish model of amyloid light chain cardiotoxicity: regeneration versus degeneration.
Mishra S, Joshi S, Ward JE, Buys EP, Mishra D, Mishra D, Morgado I, Fisch S, Lavatelli F, Merlini G, Dorbala S, MacRae CA, Liao R. Mishra S, et al. Among authors: liao r. Am J Physiol Heart Circ Physiol. 2019 May 1;316(5):H1158-H1166. doi: 10.1152/ajpheart.00788.2018. Epub 2019 Mar 15. Am J Physiol Heart Circ Physiol. 2019. PMID: 30875258 Free PMC article.
1,449 results