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Evolutionarily conserved Galphabetagamma binding surfaces support a model of the G protein-receptor complex.
Lichtarge O, Bourne HR, Cohen FE. Lichtarge O, et al. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7507-11. doi: 10.1073/pnas.93.15.7507. Proc Natl Acad Sci U S A. 1996. PMID: 8755504 Free PMC article.
Nonetheless, the locations of the receptors and effector binding sites remain poorly characterized, although nearly complete structures of the alphabetagamma heterotrimeric complex are available. Here we apply evolutionary trace (ET) analysis [Lichtarge, O., Bourne, …
Nonetheless, the locations of the receptors and effector binding sites remain poorly characterized, although nearly complete structures of t …
176 results