Lichtarge O - Search Results

1

Evolutionary predictions of binding surfaces and interactions.

Lichtarge O, Sowa ME. Lichtarge O, et al. Curr Opin Struct Biol. 2002 Feb;12(1):21-7. doi: 10.1016/s0959-440x(02)00284-1. Curr Opin Struct Biol. 2002. PMID: 11839485 Review.

2

An evolutionary trace method defines binding surfaces common to protein families.

Lichtarge O, Bourne HR, Cohen FE. Lichtarge O, et al. J Mol Biol. 1996 Mar 29;257(2):342-58. doi: 10.1006/jmbi.1996.0167. J Mol Biol. 1996. PMID: 8609628

3

Evolutionarily conserved Galphabetagamma binding surfaces support a model of the G protein-receptor complex.

Lichtarge O, Bourne HR, Cohen FE. Lichtarge O, et al. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7507-11. doi: 10.1073/pnas.93.15.7507. Proc Natl Acad Sci U S A. 1996. PMID: 8755504 Free PMC article.

Nonetheless, the locations of the receptors and effector binding sites remain poorly characterized, although nearly complete structures of the alphabetagamma heterotrimeric complex are available. Here we apply evolutionary trace (ET) analysis [Lichtarge, O., Bourne, …

Nonetheless, the locations of the receptors and effector binding sites remain poorly characterized, although nearly complete structures of t …

4

Identification of functional surfaces of the zinc binding domains of intracellular receptors.

Lichtarge O, Yamamoto KR, Cohen FE. Lichtarge O, et al. J Mol Biol. 1997 Dec 5;274(3):325-37. doi: 10.1006/jmbi.1997.1395. J Mol Biol. 1997. PMID: 9405143

5

A regulator of G protein signaling interaction surface linked to effector specificity.

Sowa ME, He W, Wensel TG, Lichtarge O. Sowa ME, et al. Among authors: lichtarge o. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1483-8. doi: 10.1073/pnas.030409597. Proc Natl Acad Sci U S A. 2000. PMID: 10677488 Free PMC article.

6

A genome-wide search for synaptic vesicle cycle proteins in Drosophila.

Lloyd TE, Verstreken P, Ostrin EJ, Phillippi A, Lichtarge O, Bellen HJ. Lloyd TE, et al. Among authors: lichtarge o. Neuron. 2000 Apr;26(1):45-50. doi: 10.1016/s0896-6273(00)81136-8. Neuron. 2000. PMID: 10798391

7

Prediction and confirmation of a site critical for effector regulation of RGS domain activity.

Sowa ME, He W, Slep KC, Kercher MA, Lichtarge O, Wensel TG. Sowa ME, et al. Among authors: lichtarge o. Nat Struct Biol. 2001 Mar;8(3):234-7. doi: 10.1038/84974. Nat Struct Biol. 2001. PMID: 11224568

8

Evolutionary traces of functional surfaces along G protein signaling pathway.

Lichtarge O, Sowa ME, Philippi A. Lichtarge O, et al. Methods Enzymol. 2002;344:536-56. doi: 10.1016/s0076-6879(02)44739-8. Methods Enzymol. 2002. PMID: 11771409 No abstract available.

9

Structural clusters of evolutionary trace residues are statistically significant and common in proteins.

Madabushi S, Yao H, Marsh M, Kristensen DM, Philippi A, Sowa ME, Lichtarge O. Madabushi S, et al. Among authors: lichtarge o. J Mol Biol. 2002 Feb 8;316(1):139-54. doi: 10.1006/jmbi.2001.5327. J Mol Biol. 2002. PMID: 11829509

10

Lysine 270 in the third intracellular domain of the oxytocin receptor is an important determinant for G alpha(q) coupling specificity.

Yang M, Wang W, Zhong M, Philippi A, Lichtarge O, Sanborn BM. Yang M, et al. Among authors: lichtarge o. Mol Endocrinol. 2002 Apr;16(4):814-23. doi: 10.1210/mend.16.4.0807. Mol Endocrinol. 2002. PMID: 11923477

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