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New tools for studying microglia in the mouse and human CNS.
Bennett ML, Bennett FC, Liddelow SA, Ajami B, Zamanian JL, Fernhoff NB, Mulinyawe SB, Bohlen CJ, Adil A, Tucker A, Weissman IL, Chang EF, Li G, Grant GA, Hayden Gephart MG, Barres BA. Bennett ML, et al. Among authors: liddelow sa. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):E1738-46. doi: 10.1073/pnas.1525528113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884166 Free PMC article.
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.
Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O'Keeffe S, Phatnani HP, Guarnieri P, Caneda C, Ruderisch N, Deng S, Liddelow SA, Zhang C, Daneman R, Maniatis T, Barres BA, Wu JQ. Zhang Y, et al. Among authors: liddelow sa. J Neurosci. 2014 Sep 3;34(36):11929-47. doi: 10.1523/JNEUROSCI.1860-14.2014. J Neurosci. 2014. PMID: 25186741 Free PMC article.
SnapShot: Astrocytes in Health and Disease.
Liddelow S, Barres B. Liddelow S, et al. Cell. 2015 Aug 27;162(5):1170-1170.e1. doi: 10.1016/j.cell.2015.08.029. Cell. 2015. PMID: 26317476 Free article.
Neurotoxic reactive astrocytes are induced by activated microglia.
Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch DH, Dawson VL, Dawson TM, Stevens B, Barres BA. Liddelow SA, et al. Nature. 2017 Jan 26;541(7638):481-487. doi: 10.1038/nature21029. Epub 2017 Jan 18. Nature. 2017. PMID: 28099414 Free PMC article.
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C; Alzheimer’s Disease Neuroimaging Initiative; Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. Shi Y, et al. Among authors: liddelow sa. Nature. 2017 Sep 28;549(7673):523-527. doi: 10.1038/nature24016. Epub 2017 Sep 20. Nature. 2017. PMID: 28959956 Free PMC article.
Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.
Vainchtein ID, Chin G, Cho FS, Kelley KW, Miller JG, Chien EC, Liddelow SA, Nguyen PT, Nakao-Inoue H, Dorman LC, Akil O, Joshita S, Barres BA, Paz JT, Molofsky AB, Molofsky AV. Vainchtein ID, et al. Among authors: liddelow sa. Science. 2018 Mar 16;359(6381):1269-1273. doi: 10.1126/science.aal3589. Epub 2018 Feb 1. Science. 2018. PMID: 29420261 Free PMC article.
Normal aging induces A1-like astrocyte reactivity.
Clarke LE, Liddelow SA, Chakraborty C, Münch AE, Heiman M, Barres BA. Clarke LE, et al. Among authors: liddelow sa. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1896-E1905. doi: 10.1073/pnas.1800165115. Epub 2018 Feb 7. Proc Natl Acad Sci U S A. 2018. PMID: 29437957 Free PMC article.
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease.
Yun SP, Kam TI, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, Mao X, Lee JH, Kumar M, An D, Kang SU, Lee Y, Lee KC, Na DH, Kim D, Lee SH, Roschke VV, Liddelow SA, Mari Z, Barres BA, Dawson VL, Lee S, Dawson TM, Ko HS. Yun SP, et al. Among authors: liddelow sa. Nat Med. 2018 Jul;24(7):931-938. doi: 10.1038/s41591-018-0051-5. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892066 Free PMC article.
89 results