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Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.
Sonoda J, Chong LW, Downes M, Barish GD, Coulter S, Liddle C, Lee CH, Evans RM. Sonoda J, et al. Among authors: liddle c. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2198-203. doi: 10.1073/pnas.0409481102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671183 Free PMC article.
Benefit of farnesoid X receptor inhibition in obstructive cholestasis.
Stedman C, Liddle C, Coulter S, Sonoda J, Alvarez JG, Evans RM, Downes M. Stedman C, et al. Among authors: liddle c. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11323-8. doi: 10.1073/pnas.0604772103. Epub 2006 Jul 14. Proc Natl Acad Sci U S A. 2006. PMID: 16844773 Free PMC article.
Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism.
Kacevska M, Downes MR, Sharma R, Evans RM, Clarke SJ, Liddle C, Robertson GR. Kacevska M, et al. Among authors: liddle c. Clin Cancer Res. 2011 May 15;17(10):3170-80. doi: 10.1158/1078-0432.CCR-10-3289. Epub 2011 Apr 15. Clin Cancer Res. 2011. PMID: 21498392 Free PMC article.
FXR and PXR: potential therapeutic targets in cholestasis.
Jonker JW, Liddle C, Downes M. Jonker JW, et al. Among authors: liddle c. J Steroid Biochem Mol Biol. 2012 Jul;130(3-5):147-58. doi: 10.1016/j.jsbmb.2011.06.012. Epub 2011 Jul 20. J Steroid Biochem Mol Biol. 2012. PMID: 21801835 Free PMC article. Review.
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β.
Cho H, Zhao X, Hatori M, Yu RT, Barish GD, Lam MT, Chong LW, DiTacchio L, Atkins AR, Glass CK, Liddle C, Auwerx J, Downes M, Panda S, Evans RM. Cho H, et al. Among authors: liddle c. Nature. 2012 Mar 29;485(7396):123-7. doi: 10.1038/nature11048. Nature. 2012. PMID: 22460952 Free PMC article.
240 results